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Study of the {sup 14}C benzimidazole distribution in mice after inter-peritoneal injection; Etude de la repartition du benzimidazole {sup 14}C chez la souris apres injection intraperitoneale

Abstract

In order to provide further information on the mechanism of benzimidazole radioprotective activity, this work studies the tissual repartition in mice of this compound labelled with carbon 14. Experiments have showed that benzimidazole distribution is fast and homogeneous in all the tissues, but however affinity appears at the level of stomach and gastric content. Elimination is made through the urinary system and is very fast. (author) [French] Dans le cadre de l'etude du mecanisme de l'action radioprotectrice du benzimidazole, ce travail a pour objet l'etude de la repartition tissulaire chez la souris de ce compose marque au carbone 14. L'experimentation a montre que le benzimidazole se repartit tres rapidement et de facon pratiquement homogene dans tous les tissus, avec toutefois une affinite paraissant se manifester au niveau de l'estomac et du contenu gastrique. L'elimination, qui se fait par voie urinaire, est tres rapide. (auteur)
Authors:
Tyortyalian, C [1] 
  1. Commissariat a l'Energie Atomique, Grenoble (France). Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1965
Product Type:
Technical Report
Report Number:
CEA-R-2899
Resource Relation:
Other Information: 8 refs; PBD: 1965
Subject:
60 APPLIED LIFE SCIENCES; AUTORADIOGRAPHY; BENZIMIDAZOLES; CARBON 14 COMPOUNDS; EXCRETION; INTRAPERITONEAL INJECTION; MICE; RADIOPROTECTIVE SUBSTANCES; SCINTILLATION COUNTING; STOMACH; TIME DEPENDENCE; TISSUE DISTRIBUTION; TRACER TECHNIQUES
OSTI ID:
20621943
Research Organizations:
CEA Grenoble, 38 (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR05R2899065594
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
15 pages
Announcement Date:
Aug 28, 2005

Citation Formats

Tyortyalian, C. Study of the {sup 14}C benzimidazole distribution in mice after inter-peritoneal injection; Etude de la repartition du benzimidazole {sup 14}C chez la souris apres injection intraperitoneale. France: N. p., 1965. Web.
Tyortyalian, C. Study of the {sup 14}C benzimidazole distribution in mice after inter-peritoneal injection; Etude de la repartition du benzimidazole {sup 14}C chez la souris apres injection intraperitoneale. France.
Tyortyalian, C. 1965. "Study of the {sup 14}C benzimidazole distribution in mice after inter-peritoneal injection; Etude de la repartition du benzimidazole {sup 14}C chez la souris apres injection intraperitoneale." France.
@misc{etde_20621943,
title = {Study of the {sup 14}C benzimidazole distribution in mice after inter-peritoneal injection; Etude de la repartition du benzimidazole {sup 14}C chez la souris apres injection intraperitoneale}
author = {Tyortyalian, C}
abstractNote = {In order to provide further information on the mechanism of benzimidazole radioprotective activity, this work studies the tissual repartition in mice of this compound labelled with carbon 14. Experiments have showed that benzimidazole distribution is fast and homogeneous in all the tissues, but however affinity appears at the level of stomach and gastric content. Elimination is made through the urinary system and is very fast. (author) [French] Dans le cadre de l'etude du mecanisme de l'action radioprotectrice du benzimidazole, ce travail a pour objet l'etude de la repartition tissulaire chez la souris de ce compose marque au carbone 14. L'experimentation a montre que le benzimidazole se repartit tres rapidement et de facon pratiquement homogene dans tous les tissus, avec toutefois une affinite paraissant se manifester au niveau de l'estomac et du contenu gastrique. L'elimination, qui se fait par voie urinaire, est tres rapide. (auteur)}
place = {France}
year = {1965}
month = {Jul}
}