Abstract
We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to the lac repressor and for a DNA containing an abasic site analog bound to the formamidopyrimidine-DNA glycosylase are reported. Experimental data are compared to predicted damage distribution obtained using the theoretical model RADACK.
Begusova, Marie;
[1]
Gillard, Nathalie;
[2]
Sy, Denise;
[2]
Castaing, Bertrand;
[2]
Charlier, Michel;
[2]
Spotheim-Maurizot, Melanie
[2]
- Department of Radiation Dosimetry, Nuclear Physics Institute, Na Truhlarce 39/64, CZ-18086, Prague 8 (Czech Republic)
- Centre de Biophysique Moleculaire, CNRS, rue Charles-Sadron, F-45071 Orleans Cedex 2 (France)
Citation Formats
Begusova, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, and Spotheim-Maurizot, Melanie.
Radiolysis of DNA-protein complexes.
United Kingdom: N. p.,
2005.
Web.
doi:10.1016/j.radphyschem.2004.01.009.
Begusova, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, & Spotheim-Maurizot, Melanie.
Radiolysis of DNA-protein complexes.
United Kingdom.
https://doi.org/10.1016/j.radphyschem.2004.01.009
Begusova, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, and Spotheim-Maurizot, Melanie.
2005.
"Radiolysis of DNA-protein complexes."
United Kingdom.
https://doi.org/10.1016/j.radphyschem.2004.01.009.
@misc{etde_20620250,
title = {Radiolysis of DNA-protein complexes}
author = {Begusova, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, and Spotheim-Maurizot, Melanie}
abstractNote = {We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to the lac repressor and for a DNA containing an abasic site analog bound to the formamidopyrimidine-DNA glycosylase are reported. Experimental data are compared to predicted damage distribution obtained using the theoretical model RADACK.}
doi = {10.1016/j.radphyschem.2004.01.009}
journal = []
issue = {2-3}
volume = {72}
journal type = {AC}
place = {United Kingdom}
year = {2005}
month = {Feb}
}
title = {Radiolysis of DNA-protein complexes}
author = {Begusova, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, and Spotheim-Maurizot, Melanie}
abstractNote = {We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to the lac repressor and for a DNA containing an abasic site analog bound to the formamidopyrimidine-DNA glycosylase are reported. Experimental data are compared to predicted damage distribution obtained using the theoretical model RADACK.}
doi = {10.1016/j.radphyschem.2004.01.009}
journal = []
issue = {2-3}
volume = {72}
journal type = {AC}
place = {United Kingdom}
year = {2005}
month = {Feb}
}