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In vivo measurements of EPR signals in whole human teeth

Abstract

Low-frequency EPR has the potential advantage of making accurate and sensitive measurements of absorbed radiation dose in teeth in situ. We report here on measurements within the human mouth in volunteers using 1200 MHz EPR, with an irradiated tooth in a special holder. We obtained a signal/noise ratio within 50% of that seen when the same sample was measured extraorally. The intraoral signal/noise can be improved and can be reduced further with optimization of conditions and use of more specifically designed and optimized resonators that fit within the mouth, probing 1-4 teeth, and can make the measurements in molars or incisors. The presence of amalgam fillings did not significantly impact the accuracy of measurements in those teeth or in adjacent teeth. These initial results make us optimistic that intra-oral measurements of the teeth will be feasible for accurate determination of exposures over the whole range in which acute clinical effects are possible.
Authors:
Iwasaki, Akinori; [1]  Grinberg, Oleg; [1]  Walczak, Tadeusz; [1]  Swartz, Harold M [1] 
  1. Department of Radiology, Dartmouth Medical School, 702 Vail, Hanover, NH 03755 (United States)
Publication Date:
Feb 01, 2005
Product Type:
Journal Article
Resource Relation:
Journal Name: Applied Radiation and Isotopes; Journal Volume: 62; Journal Issue: 2; Conference: 6. international symposium on ESR dosimetry and applications, Campos do Jordao (Brazil), 12-16 Oct 2003; Other Information: DOI: 10.1016/j.apradiso.2004.08.042; PII: S0969-8043(04)00459-2; Copyright (c) 2004 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); PBD: Feb 2005
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; ACCURACY; DOSIMETRY; ELECTRON SPIN RESONANCE; GHZ RANGE 01-100; HUMAN POPULATIONS; IN VIVO; IRRADIATION; MERCURY ALLOYS; RADIATION DOSES; RESONATORS; SIGNAL-TO-NOISE RATIO; TEETH
OSTI ID:
20620155
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0969-8043; ARISEF; TRN: GB05R1343063805
Submitting Site:
GBN
Size:
page(s) 187-190
Announcement Date:
Aug 28, 2005

Citation Formats

Iwasaki, Akinori, Grinberg, Oleg, Walczak, Tadeusz, and Swartz, Harold M. In vivo measurements of EPR signals in whole human teeth. United Kingdom: N. p., 2005. Web. doi:10.1016/j.apradiso.2004.08.042.
Iwasaki, Akinori, Grinberg, Oleg, Walczak, Tadeusz, & Swartz, Harold M. In vivo measurements of EPR signals in whole human teeth. United Kingdom. https://doi.org/10.1016/j.apradiso.2004.08.042
Iwasaki, Akinori, Grinberg, Oleg, Walczak, Tadeusz, and Swartz, Harold M. 2005. "In vivo measurements of EPR signals in whole human teeth." United Kingdom. https://doi.org/10.1016/j.apradiso.2004.08.042.
@misc{etde_20620155,
title = {In vivo measurements of EPR signals in whole human teeth}
author = {Iwasaki, Akinori, Grinberg, Oleg, Walczak, Tadeusz, and Swartz, Harold M}
abstractNote = {Low-frequency EPR has the potential advantage of making accurate and sensitive measurements of absorbed radiation dose in teeth in situ. We report here on measurements within the human mouth in volunteers using 1200 MHz EPR, with an irradiated tooth in a special holder. We obtained a signal/noise ratio within 50% of that seen when the same sample was measured extraorally. The intraoral signal/noise can be improved and can be reduced further with optimization of conditions and use of more specifically designed and optimized resonators that fit within the mouth, probing 1-4 teeth, and can make the measurements in molars or incisors. The presence of amalgam fillings did not significantly impact the accuracy of measurements in those teeth or in adjacent teeth. These initial results make us optimistic that intra-oral measurements of the teeth will be feasible for accurate determination of exposures over the whole range in which acute clinical effects are possible.}
doi = {10.1016/j.apradiso.2004.08.042}
journal = []
issue = {2}
volume = {62}
journal type = {AC}
place = {United Kingdom}
year = {2005}
month = {Feb}
}