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Readout and characterisation of new silicon pixel photodiode array for use in PET

Abstract

Full text: Positron emission tomography (PET) is a functional imaging tool, which is able to quantify physiological, and biochemical processes in vivo using short-lived cyclotron-produced radiotracers. The main physical principle of PET is the simultaneous measurement of two 511 keV photons which are emitted in opposite directions following the annihilation of a positron in tissue. The accuracy of tracking these photons determines the accuracy of localising the radiotracer in the body, which is referred to as the spatial resolution of the system. Compared with conventional single photon imaging with gamma cameras, PET provides superior spatial resolution and sensitivity. However, compared with anatomical imaging techniques, the spatial resolution remains relatively poor at approximately 4-6 mm full width at half maximum (FWHM), compared with 1 mm FWHM for MRI. The Centre for Medical Radiation Physics at the University of Wollongong is developing a new Positron Emission Tomography (PET) detection sub-module that will significantly improve the spatial resolution of PET. The new sub-module design is simple and robust to minimise module assembly complications and is completely independent of photomultiplier tubes. The new sub-module has also been designed to maximise its flexibility for easy sub-module coupling so as to form a complete, customised, detection  More>>
Authors:
Hooper, P; Ward, G; Lerch, R; Rozenfeld, A; [1]  Moorehead, G; Taylor, G; [2]  Pervertailo, V [3] 
  1. University of Wollongong, NSW (Australia). Center for Medical Radiation Physics
  2. University of Melbourne, VIC (Australia). High Energy Physics Department
  3. SPA BIT, (Ukraine)
Publication Date:
Jul 01, 2002
Product Type:
Conference
Resource Relation:
Conference: 15. Biennial Congress of the Australian Institute of Physics. Physics and industry working together, Sydney, NSW (Australia), 8-11 Jul 2002; Other Information: PBD: 2002; Related Information: In: 15th Biennial Congress of the Australian Institute of Physics incorporating Australian Conference of Optical Fibre Technology (ACOFT) and Australian Optical Society (AOS). Handbook and abstracts, 235 pages.
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ALPHA PARTICLES; ANNIHILATION; CESIUM 137; CESIUM IODIDES; COMPARATIVE EVALUATIONS; COMPUTERIZED CONTROL SYSTEMS; CYCLOTRONS; DOPED MATERIALS; GAMMA CAMERAS; GAMMA DETECTION; GAMMA SPECTROSCOPY; IN VIVO; KEV RANGE 100-1000; NMR IMAGING; PHOTONS; POLONIUM 210; POSITRON COMPUTED TOMOGRAPHY; POSITRONS; RADIATION DETECTION; READOUT SYSTEMS; SCINTILLATION COUNTING; SENSITIVITY; SILICON; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SPATIAL RESOLUTION; THALLIUM
OSTI ID:
20619955
Research Organizations:
Australian Institute of Physics (Australia)
Country of Origin:
Australia
Language:
English
Other Identifying Numbers:
TRN: AU0524633063605
Availability:
Available in abstract form only, full text entered in this record
Submitting Site:
INIS
Size:
page(s) 223
Announcement Date:
Aug 28, 2005

Citation Formats

Hooper, P, Ward, G, Lerch, R, Rozenfeld, A, Moorehead, G, Taylor, G, and Pervertailo, V. Readout and characterisation of new silicon pixel photodiode array for use in PET. Australia: N. p., 2002. Web.
Hooper, P, Ward, G, Lerch, R, Rozenfeld, A, Moorehead, G, Taylor, G, & Pervertailo, V. Readout and characterisation of new silicon pixel photodiode array for use in PET. Australia.
Hooper, P, Ward, G, Lerch, R, Rozenfeld, A, Moorehead, G, Taylor, G, and Pervertailo, V. 2002. "Readout and characterisation of new silicon pixel photodiode array for use in PET." Australia.
@misc{etde_20619955,
title = {Readout and characterisation of new silicon pixel photodiode array for use in PET}
author = {Hooper, P, Ward, G, Lerch, R, Rozenfeld, A, Moorehead, G, Taylor, G, and Pervertailo, V}
abstractNote = {Full text: Positron emission tomography (PET) is a functional imaging tool, which is able to quantify physiological, and biochemical processes in vivo using short-lived cyclotron-produced radiotracers. The main physical principle of PET is the simultaneous measurement of two 511 keV photons which are emitted in opposite directions following the annihilation of a positron in tissue. The accuracy of tracking these photons determines the accuracy of localising the radiotracer in the body, which is referred to as the spatial resolution of the system. Compared with conventional single photon imaging with gamma cameras, PET provides superior spatial resolution and sensitivity. However, compared with anatomical imaging techniques, the spatial resolution remains relatively poor at approximately 4-6 mm full width at half maximum (FWHM), compared with 1 mm FWHM for MRI. The Centre for Medical Radiation Physics at the University of Wollongong is developing a new Positron Emission Tomography (PET) detection sub-module that will significantly improve the spatial resolution of PET. The new sub-module design is simple and robust to minimise module assembly complications and is completely independent of photomultiplier tubes. The new sub-module has also been designed to maximise its flexibility for easy sub-module coupling so as to form a complete, customised, detection module to be used in PET scanners dedicated to human brain and breast, and small animal studies. A new computer controlled gantry allows the system to be used for PET and SPECT applications. Silicon 8x8 detector arrays have been developed by CMRP and will be optically coupled scintillation crystals and readout using the VIKING{sup tM} hybrid preamplifier chip to form the basis of the new module Characterisation of the pixel photodiode array has been performed to check the uniformity of the response of the array. This characterisation has been done using a pulsed, near infra-red laser diode system and alpha particles from a {sup 210}Po source. We have also coupled individual 3x3x3 mm{sup 3} thallium-doped caesium iodide CsI(TI) scintillator crystals to the array and performed successful gamma ray spectroscopy experiments from a {sup 137}Cs source.}
place = {Australia}
year = {2002}
month = {Jul}
}