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MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility

Abstract

Full text: We have developed an innovative on-line MOSFET readout system for use in the quality assurance of radiation treatment beams. Recently the system has found application in areas where excellent spatial resolution is also a requirement in the quality assurance process, for example IMRT, and microbeam radiation therapy. The excellent spatial resolution is achieved by using a quadruple RADFET{sup TM} chip in 'edge on' mode. In developing this approach we have found that the system can be utilised to determine any error in the beam profile measurements due to misalignment of RADFET with respect to the radiation beam or microbeam. Using this approach will ensure that the excellent spatial resolution of the RADFET used in 'edge-on' mode is fully utilised. In this work we report on dosimetry measurements performed at the microbeam radiation therapy beamline located at the European Synchrotron Radiation Facility. The synchrotron planar array microbeam with size 10-30 {mu}m and pitch {approx}200 {mu}m has found an important application in microbeam radiation therapy (MRT) of brain tumours in infants for whom other kinds of radiotherapy are inadequate and/or unsafe. The radiation damage from an array of parallel microbeams correlates strongly with the range of peak-valley dose ratios (PVDR),  More>>
Authors:
Rozenfeld, A; Lerch, M; [1]  Brauer-Krisch, E; Bravin, A; Di Michiel, M [2] 
  1. University of Wollongong, NSW (Australia). Center for Medical Radiation Physics
  2. European Synchrotron Radiation Facility, Grenoble, (France)
Publication Date:
Jul 01, 2002
Product Type:
Conference
Resource Relation:
Conference: 15. Biennial Congress of the Australian Institute of Physics. Physics and industry working together, Sydney, NSW (Australia), 8-11 Jul 2002; Other Information: PBD: 2002; Related Information: In: 15th Biennial Congress of the Australian Institute of Physics incorporating Australian Conference of Optical Fibre Technology (ACOFT) and Australian Optical Society (AOS). Handbook and abstracts, 235 pages.
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; BEAM OPTICS; BEAM PROFILES; BRAIN; COMPUTERIZED SIMULATION; DOSE-RESPONSE RELATIONSHIPS; DOSIMETRY; ERRORS; EUROPEAN SYNCHROTRON RADIATION FACILITY; FILM DOSIMETRY; INFANTS; MONTE CARLO METHOD; ON-LINE SYSTEMS; PHANTOMS; QUALITY ASSURANCE; RADIATION DOSES; RADIOTHERAPY; READOUT SYSTEMS; SPATIAL RESOLUTION
OSTI ID:
20619867
Research Organizations:
Australian Institute of Physics (Australia)
Country of Origin:
Australia
Language:
English
Other Identifying Numbers:
TRN: AU0524545063517
Availability:
Available in abstract form only, full text entered in this record
Submitting Site:
INIS
Size:
page(s) 144
Announcement Date:
Aug 28, 2005

Citation Formats

Rozenfeld, A, Lerch, M, Brauer-Krisch, E, Bravin, A, and Di Michiel, M. MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility. Australia: N. p., 2002. Web.
Rozenfeld, A, Lerch, M, Brauer-Krisch, E, Bravin, A, & Di Michiel, M. MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility. Australia.
Rozenfeld, A, Lerch, M, Brauer-Krisch, E, Bravin, A, and Di Michiel, M. 2002. "MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility." Australia.
@misc{etde_20619867,
title = {MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility}
author = {Rozenfeld, A, Lerch, M, Brauer-Krisch, E, Bravin, A, and Di Michiel, M}
abstractNote = {Full text: We have developed an innovative on-line MOSFET readout system for use in the quality assurance of radiation treatment beams. Recently the system has found application in areas where excellent spatial resolution is also a requirement in the quality assurance process, for example IMRT, and microbeam radiation therapy. The excellent spatial resolution is achieved by using a quadruple RADFET{sup TM} chip in 'edge on' mode. In developing this approach we have found that the system can be utilised to determine any error in the beam profile measurements due to misalignment of RADFET with respect to the radiation beam or microbeam. Using this approach will ensure that the excellent spatial resolution of the RADFET used in 'edge-on' mode is fully utilised. In this work we report on dosimetry measurements performed at the microbeam radiation therapy beamline located at the European Synchrotron Radiation Facility. The synchrotron planar array microbeam with size 10-30 {mu}m and pitch {approx}200 {mu}m has found an important application in microbeam radiation therapy (MRT) of brain tumours in infants for whom other kinds of radiotherapy are inadequate and/or unsafe. The radiation damage from an array of parallel microbeams correlates strongly with the range of peak-valley dose ratios (PVDR), ie, the range of the ratio of the absorbed dose to tissue directly in line with the mid-plane of the microbeam to that in the mid-plane between adjacent microbeams. Novel physical dosimetry of the microbeams using the online MOSFET reader system will be presented. Comparison of the experimental results with both GaF film measurements and Monte Carlo computer-simulated dosimetry are described here for selected points in the peak and valley regions of a microbeam-irradiated tissue phantom.}
place = {Australia}
year = {2002}
month = {Jul}
}