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Physical model of the haemodynamic effects around the obstructing plaque in the acute coronary syndromes take account of the stenosis geometry

Abstract

Selective coronary angiography with quantitative parameter assessment of the vessel stenosis geometry, which leads to acute coronary syndrome, was performed in 205 patients undergoing acute phase of myocardial infarction or unstable angina pectoris. Data for physicomechanical properties of the arterial vessels, blood and blood flow were used. The range of pressure variations accompanying the most frequently encountered ruptures of the atherosclerotic plaques was analyzed with physical model. It suggests that in 'lock' type plaques the ratio between the pressure on the wall of the normal vessel and that in the section outside the stenosis is considerably increased, especially in cases of enlarged vessel gauge. The results obtained show that the wall pressure closely to the plaque of a stenosed vessel with normal diameter of 3.5 mm exceeds 25 times the pressure within a normal vessel segment. (author)
Authors:
Matveev, M [1] 
  1. Bulgarian Academy of Sciences, Centre of Biomedical Engineering, Sofia (Bulgaria)
Publication Date:
Jul 01, 2004
Product Type:
Conference
Report Number:
INIS-BG-0910
Resource Relation:
Conference: 9. National Conference on Biomedical Physics and Engineering, Sofia (Bulgaria), 14-16 Oct 2004; Other Information: 2 figs., 1 tab., 11 refs; PBD: 2004
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIOSCLEROSIS; BIOMEDICAL RADIOGRAPHY; BLOOD; BLOOD FLOW; BLOOD VESSELS; CORONARIES; PATIENTS
OSTI ID:
20619505
Country of Origin:
Bulgaria
Language:
English
Other Identifying Numbers:
TRN: BG0500159063045
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
4 pages
Announcement Date:
Aug 21, 2005

Citation Formats

Matveev, M. Physical model of the haemodynamic effects around the obstructing plaque in the acute coronary syndromes take account of the stenosis geometry. Bulgaria: N. p., 2004. Web.
Matveev, M. Physical model of the haemodynamic effects around the obstructing plaque in the acute coronary syndromes take account of the stenosis geometry. Bulgaria.
Matveev, M. 2004. "Physical model of the haemodynamic effects around the obstructing plaque in the acute coronary syndromes take account of the stenosis geometry." Bulgaria.
@misc{etde_20619505,
title = {Physical model of the haemodynamic effects around the obstructing plaque in the acute coronary syndromes take account of the stenosis geometry}
author = {Matveev, M}
abstractNote = {Selective coronary angiography with quantitative parameter assessment of the vessel stenosis geometry, which leads to acute coronary syndrome, was performed in 205 patients undergoing acute phase of myocardial infarction or unstable angina pectoris. Data for physicomechanical properties of the arterial vessels, blood and blood flow were used. The range of pressure variations accompanying the most frequently encountered ruptures of the atherosclerotic plaques was analyzed with physical model. It suggests that in 'lock' type plaques the ratio between the pressure on the wall of the normal vessel and that in the section outside the stenosis is considerably increased, especially in cases of enlarged vessel gauge. The results obtained show that the wall pressure closely to the plaque of a stenosed vessel with normal diameter of 3.5 mm exceeds 25 times the pressure within a normal vessel segment. (author)}
place = {Bulgaria}
year = {2004}
month = {Jul}
}