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Heterogeneous planning for homogeneous protocols

Abstract

Clinical trials often require homogeneous treatment plans. Many institutions, however, have begun using heterogeneous plans. Is it possible to satisfy the requirements of such a protocol while achieving the superior accuracy of heterogeneous treatment planning? At the University of Texas M. D. Anderson Cancer Center, we currently use conformal treatment planning with heterogeneities for thoracic cancers. This paper describes a procedure that has been developed to satisfy the requirements of a homogeneous protocol, such as RTOG 98-01 (A Phase III Study of Amifostine mucosal protection), while maintaining accuracy in treatment planning.
Publication Date:
Jun 30, 2004
Product Type:
Journal Article
Resource Relation:
Journal Name: Medical Dosimetry; Journal Volume: 29; Journal Issue: 2; Other Information: DOI: 10.1016/j.meddos.2004.03.006; PII: S0958394704000366; Copyright (c) 2004 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); PBD: Sum 2004
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; ACCURACY; CLINICAL TRIALS; NEOPLASMS; PLANNING; RADIOTHERAPY; SAFETY
OSTI ID:
20619430
Country of Origin:
United States
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0739-0211; MEDOEJ; TRN: US05R2439062935
Submitting Site:
INIS
Size:
page(s) 80-84
Announcement Date:
Aug 21, 2005

Citation Formats

Brooks, Chris, Starkschall, George, Famiglietti, Robin, Cox, James, Frank, Steven, Komaki, Ritsuko, Zhongxing, Liao, Stevens, Craig, and Forster, Kenneth. Heterogeneous planning for homogeneous protocols. United States: N. p., 2004. Web. doi:10.1016/j.meddos.2004.03.006.
Brooks, Chris, Starkschall, George, Famiglietti, Robin, Cox, James, Frank, Steven, Komaki, Ritsuko, Zhongxing, Liao, Stevens, Craig, & Forster, Kenneth. Heterogeneous planning for homogeneous protocols. United States. https://doi.org/10.1016/j.meddos.2004.03.006
Brooks, Chris, Starkschall, George, Famiglietti, Robin, Cox, James, Frank, Steven, Komaki, Ritsuko, Zhongxing, Liao, Stevens, Craig, and Forster, Kenneth. 2004. "Heterogeneous planning for homogeneous protocols." United States. https://doi.org/10.1016/j.meddos.2004.03.006.
@misc{etde_20619430,
title = {Heterogeneous planning for homogeneous protocols}
author = {Brooks, Chris, Starkschall, George, Famiglietti, Robin, Cox, James, Frank, Steven, Komaki, Ritsuko, Zhongxing, Liao, Stevens, Craig, and Forster, Kenneth}
abstractNote = {Clinical trials often require homogeneous treatment plans. Many institutions, however, have begun using heterogeneous plans. Is it possible to satisfy the requirements of such a protocol while achieving the superior accuracy of heterogeneous treatment planning? At the University of Texas M. D. Anderson Cancer Center, we currently use conformal treatment planning with heterogeneities for thoracic cancers. This paper describes a procedure that has been developed to satisfy the requirements of a homogeneous protocol, such as RTOG 98-01 (A Phase III Study of Amifostine mucosal protection), while maintaining accuracy in treatment planning.}
doi = {10.1016/j.meddos.2004.03.006}
journal = []
issue = {2}
volume = {29}
journal type = {AC}
place = {United States}
year = {2004}
month = {Jun}
}