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Optimization of the primary collimator settings for fractionated IMRT stereotactic radiotherapy

Abstract

Advances in field-shaping techniques for stereotactic radiosurgery/radiotherapy have allowed dynamic adjustment of field shape with gantry rotation (dynamic conformal arc) in an effort to minimize dose to critical structures. Recent work evaluated the potential for increased sparing of dose to normal tissues when the primary collimator setting is optimized to only the size necessary to cover the largest shape of the dynamic micro multi leaf field. Intensity-modulated radiotherapy (IMRT) is now a treatment option for patients receiving stereotactic radiotherapy treatments. This multisegmentation of the dose delivered through multiple fixed treatment fields provides for delivery of uniform dose to the tumor volume while allowing sparing of critical structures, particularly for patients whose tumor volumes are less suited for rotational treatment. For these segmented fields, the total number of monitor units (MUs) delivered may be much greater than the number of MUs required if dose delivery occurred through an unmodulated treatment field. As a result, undesired dose delivered, as leakage through the leaves to tissues outside the area of interest, will be proportionally increased. This work will evaluate the role of optimization of the primary collimator setting for these IMRT treatment fields, and compare these results to treatment fields where the primary  More>>
Publication Date:
Jun 30, 2004
Product Type:
Journal Article
Resource Relation:
Journal Name: Medical Dosimetry; Journal Volume: 29; Journal Issue: 2; Other Information: DOI: 10.1016/j.meddos.2004.03.007; PII: S0958394704000378; Copyright (c) 2004 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); PBD: Sum 2004
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; COLLIMATORS; NEOPLASMS; OPTIMIZATION; PATIENTS; RADIATION DOSES; RADIOTHERAPY; SURGERY
OSTI ID:
20619429
Country of Origin:
United States
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0739-0211; MEDOEJ; TRN: US05R2438062934
Submitting Site:
INIS
Size:
page(s) 72-79
Announcement Date:
Aug 21, 2005

Citation Formats

Tobler, Matt, Leavitt, Dennis D, and Watson, Gordon. Optimization of the primary collimator settings for fractionated IMRT stereotactic radiotherapy. United States: N. p., 2004. Web. doi:10.1016/j.meddos.2004.03.007.
Tobler, Matt, Leavitt, Dennis D, & Watson, Gordon. Optimization of the primary collimator settings for fractionated IMRT stereotactic radiotherapy. United States. https://doi.org/10.1016/j.meddos.2004.03.007
Tobler, Matt, Leavitt, Dennis D, and Watson, Gordon. 2004. "Optimization of the primary collimator settings for fractionated IMRT stereotactic radiotherapy." United States. https://doi.org/10.1016/j.meddos.2004.03.007.
@misc{etde_20619429,
title = {Optimization of the primary collimator settings for fractionated IMRT stereotactic radiotherapy}
author = {Tobler, Matt, Leavitt, Dennis D, and Watson, Gordon}
abstractNote = {Advances in field-shaping techniques for stereotactic radiosurgery/radiotherapy have allowed dynamic adjustment of field shape with gantry rotation (dynamic conformal arc) in an effort to minimize dose to critical structures. Recent work evaluated the potential for increased sparing of dose to normal tissues when the primary collimator setting is optimized to only the size necessary to cover the largest shape of the dynamic micro multi leaf field. Intensity-modulated radiotherapy (IMRT) is now a treatment option for patients receiving stereotactic radiotherapy treatments. This multisegmentation of the dose delivered through multiple fixed treatment fields provides for delivery of uniform dose to the tumor volume while allowing sparing of critical structures, particularly for patients whose tumor volumes are less suited for rotational treatment. For these segmented fields, the total number of monitor units (MUs) delivered may be much greater than the number of MUs required if dose delivery occurred through an unmodulated treatment field. As a result, undesired dose delivered, as leakage through the leaves to tissues outside the area of interest, will be proportionally increased. This work will evaluate the role of optimization of the primary collimator setting for these IMRT treatment fields, and compare these results to treatment fields where the primary collimator settings have not been optimized.}
doi = {10.1016/j.meddos.2004.03.007}
journal = []
issue = {2}
volume = {29}
journal type = {AC}
place = {United States}
year = {2004}
month = {Jun}
}