Abstract
Objective: To study on the radioprotective effect of genistein on {gamma}-ray induced injury and to provide an experimental basis for the development of genistein. Methods: Male mice were fed with feedstuff which added by different does of genistein or normal diet for 2 weeks, and then irradiated once with 7.5 Gy {gamma}-rays and the difference in survival rates was observed; irradiated once with 4.0 Gy {gamma}-rays and the changes in blood cells were counted by usual method and the rates of micronuclei were determined. Results: The 30-day survival rate, blood cell counts of genistein-protected mice were all much higher than those of the control group, the protection factor reached 1.44, the rates of micronuclei of genistein-treated mice were much lower than that of control group. Conclusion: Genistein has significant radioprotective effect in mice.
Jianquan, Wu;
Hong, Jin;
Zhiqin, Xu;
Xianyuan, Wang;
Wenkao, Nan;
Peibing, Li
[1]
- Academy of Military Medical Sciences, Tianjin (China). Inst. of Hygiene and Environmental Medicine
Citation Formats
Jianquan, Wu, Hong, Jin, Zhiqin, Xu, Xianyuan, Wang, Wenkao, Nan, and Peibing, Li.
The experimental study on radioprotective effect of genistein.
China: N. p.,
2004.
Web.
Jianquan, Wu, Hong, Jin, Zhiqin, Xu, Xianyuan, Wang, Wenkao, Nan, & Peibing, Li.
The experimental study on radioprotective effect of genistein.
China.
Jianquan, Wu, Hong, Jin, Zhiqin, Xu, Xianyuan, Wang, Wenkao, Nan, and Peibing, Li.
2004.
"The experimental study on radioprotective effect of genistein."
China.
@misc{etde_20597494,
title = {The experimental study on radioprotective effect of genistein}
author = {Jianquan, Wu, Hong, Jin, Zhiqin, Xu, Xianyuan, Wang, Wenkao, Nan, and Peibing, Li}
abstractNote = {Objective: To study on the radioprotective effect of genistein on {gamma}-ray induced injury and to provide an experimental basis for the development of genistein. Methods: Male mice were fed with feedstuff which added by different does of genistein or normal diet for 2 weeks, and then irradiated once with 7.5 Gy {gamma}-rays and the difference in survival rates was observed; irradiated once with 4.0 Gy {gamma}-rays and the changes in blood cells were counted by usual method and the rates of micronuclei were determined. Results: The 30-day survival rate, blood cell counts of genistein-protected mice were all much higher than those of the control group, the protection factor reached 1.44, the rates of micronuclei of genistein-treated mice were much lower than that of control group. Conclusion: Genistein has significant radioprotective effect in mice.}
journal = []
issue = {3}
volume = {13}
journal type = {AC}
place = {China}
year = {2004}
month = {Sep}
}
title = {The experimental study on radioprotective effect of genistein}
author = {Jianquan, Wu, Hong, Jin, Zhiqin, Xu, Xianyuan, Wang, Wenkao, Nan, and Peibing, Li}
abstractNote = {Objective: To study on the radioprotective effect of genistein on {gamma}-ray induced injury and to provide an experimental basis for the development of genistein. Methods: Male mice were fed with feedstuff which added by different does of genistein or normal diet for 2 weeks, and then irradiated once with 7.5 Gy {gamma}-rays and the difference in survival rates was observed; irradiated once with 4.0 Gy {gamma}-rays and the changes in blood cells were counted by usual method and the rates of micronuclei were determined. Results: The 30-day survival rate, blood cell counts of genistein-protected mice were all much higher than those of the control group, the protection factor reached 1.44, the rates of micronuclei of genistein-treated mice were much lower than that of control group. Conclusion: Genistein has significant radioprotective effect in mice.}
journal = []
issue = {3}
volume = {13}
journal type = {AC}
place = {China}
year = {2004}
month = {Sep}
}