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Comparative evaluation of nose-only vs. whole-body inhalation exposures for rats

Abstract

Two types of rat exposure chambers, nose-only and whole-body chambers, were evaluated simultaneously for the temporal and spatial distribution of the same test aerosols within the chambers, both with and without animals present. Results indicated that both types of exposure chambers performed well, with coefficients of variation less than 10% for both temporal and spatial variations. (author)0.
Publication Date:
Dec 01, 1988
Product Type:
Technical Report
Report Number:
LMF-121; INIS-XA-N-170
Resource Relation:
Other Information: 5 refs, 5 figs, 2 tabs; PBD: Dec 1988; Related Information: In: Inhalation Toxicology Research Institute annual report 1987-1988, by Mauderly, J.L.; Mewhinney, J.A.; Bechtold, W.E.; Sun, J.D.; Coons, T.A. (eds.), 659 pages.
Subject:
60 APPLIED LIFE SCIENCES; AEROSOLS; EXPOSURE CHAMBERS; INHALATION; NOSE; RATS; SPATIAL DISTRIBUTION; WHOLE-BODY IRRADIATION
Sponsoring Organizations:
Office of Health and Environmental Research, U.S. Department of Energy (United States)
OSTI ID:
20547766
Research Organizations:
Inhalation Toxicology Research Institute, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM (United States)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: Contract DE-AC04-76EV01013; TRN: XA04N1332003596
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
page(s) 58-64
Announcement Date:

Citation Formats

Yeh, H C, Snipes, M B, Eidson, A F, and Hobbs, C H. Comparative evaluation of nose-only vs. whole-body inhalation exposures for rats. IAEA: N. p., 1988. Web.
Yeh, H C, Snipes, M B, Eidson, A F, & Hobbs, C H. Comparative evaluation of nose-only vs. whole-body inhalation exposures for rats. IAEA.
Yeh, H C, Snipes, M B, Eidson, A F, and Hobbs, C H. 1988. "Comparative evaluation of nose-only vs. whole-body inhalation exposures for rats." IAEA.
@misc{etde_20547766,
title = {Comparative evaluation of nose-only vs. whole-body inhalation exposures for rats}
author = {Yeh, H C, Snipes, M B, Eidson, A F, and Hobbs, C H}
abstractNote = {Two types of rat exposure chambers, nose-only and whole-body chambers, were evaluated simultaneously for the temporal and spatial distribution of the same test aerosols within the chambers, both with and without animals present. Results indicated that both types of exposure chambers performed well, with coefficients of variation less than 10% for both temporal and spatial variations. (author)0.}
place = {IAEA}
year = {1988}
month = {Dec}
}