You need JavaScript to view this

Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain

Abstract

Using a whole-body counter, the authors have studied {sup 59}Fe absorption and loss in 8 normal subjects and in 30 iron deficient patients. Results showed that whole-body counting provided an excellent and simple method for iron retention measurements, obviating many inaccuracies of previous technic. Normal absorption of radio iron with this procedure has ranged from 9 per cent to 20 per cent of the administered tracer in normal subjects, with a mean of 15 per cent. A significant increase in {sup 59}Fe absorption was noted in 21 iron-deficient patients in whom the retention ranged from 40 to 100 per cent. However, 3 iron-deficient patients were found to have low absorption, and their severe iron deficiency could be correlated with this defect in absorption. This method permits also the determination of the rate of iron excretion during the following months and therefore the study of the mechanism of some pathological loss. (authors) [French] L'utilisation de la methode de comptage humain global a permis aux auteurs d'etudier l'absorption et l'excretion du fer-59 chez 8 sujets temoins et 30 sujets hyposideremiques. Les resultats montrent que cette technique simple et directe offre de nombreux avantages sur les methodes employees jusqu'a maintenant pour cette determination.  More>>
Authors:
Hollard, D; Benabid, Y; Berard, M; Bonnin, J; Darnault, J; Millet, M [1] 
  1. Commissariat a l'Energie Atomique, Grenoble (France). Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1969
Product Type:
Technical Report
Report Number:
CEA-R-3542
Resource Relation:
Other Information: 29 refs; PBD: 1969
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSTIC TECHNIQUES; IRON; IRON 59; NUCLEAR MEDICINE; NUTRITIONAL DEFICIENCY; RADIONUCLIDE KINETICS; RADIOPHARMACEUTICALS; TRACER TECHNIQUES
OSTI ID:
20523326
Research Organizations:
CEA Grenoble, 38 (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR04R3542091381
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
[20] pages
Announcement Date:

Citation Formats

Hollard, D, Benabid, Y, Berard, M, Bonnin, J, Darnault, J, and Millet, M. Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain. France: N. p., 1969. Web.
Hollard, D, Benabid, Y, Berard, M, Bonnin, J, Darnault, J, & Millet, M. Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain. France.
Hollard, D, Benabid, Y, Berard, M, Bonnin, J, Darnault, J, and Millet, M. 1969. "Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain." France.
@misc{etde_20523326,
title = {Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain}
author = {Hollard, D, Benabid, Y, Berard, M, Bonnin, J, Darnault, J, and Millet, M}
abstractNote = {Using a whole-body counter, the authors have studied {sup 59}Fe absorption and loss in 8 normal subjects and in 30 iron deficient patients. Results showed that whole-body counting provided an excellent and simple method for iron retention measurements, obviating many inaccuracies of previous technic. Normal absorption of radio iron with this procedure has ranged from 9 per cent to 20 per cent of the administered tracer in normal subjects, with a mean of 15 per cent. A significant increase in {sup 59}Fe absorption was noted in 21 iron-deficient patients in whom the retention ranged from 40 to 100 per cent. However, 3 iron-deficient patients were found to have low absorption, and their severe iron deficiency could be correlated with this defect in absorption. This method permits also the determination of the rate of iron excretion during the following months and therefore the study of the mechanism of some pathological loss. (authors) [French] L'utilisation de la methode de comptage humain global a permis aux auteurs d'etudier l'absorption et l'excretion du fer-59 chez 8 sujets temoins et 30 sujets hyposideremiques. Les resultats montrent que cette technique simple et directe offre de nombreux avantages sur les methodes employees jusqu'a maintenant pour cette determination. La valeur normale de l'absorption du fer chez les temoins est d'environ 15 pour cent de la dose ingeree. Ce chiffre est tres fortement augmente chez 21 sujets hyposideremiques, pouvant atteindre 100 pour cent de la dose ingeree. Par contre, pour 3 malades, cette absorption est si faible qu'elle suggere une carence par defaut d'absorption. Cette methode permet egalement de suivre l'excretion du fer au cours des mois qui suivent l'examen et de determiner le mecanisme de fuites anormales. (auteurs)}
place = {France}
year = {1969}
month = {Jul}
}