Abstract
Helicobacter pylori infection is one of the most common bacterial infection (82 %) in Senegal where malnutrition is common in children (25 %). Our aims were to definite prevalence of H. pylori, to determine the relationship between Hp infection and undernourishment and to verify the efficiency of treatment with probiotic. In some studies a positive effect of Saccharomyces boulardii has been demonstrated against H. pylori. We have included healthy children 7 to 10 years of age. 108 out of 129 (84%) were H. pylori-positive by breath-test. Two groups were randomised. Group A was treated with ten days' standard triple therapy (Omeprazole 1 mg Kg/day in single day gift, Amoxycillin 50 mg/kg/two times per day and Clarithromycin 250 mg two times per day). Group B received probiotic (250 mg of Saccharomyces boulardii with 5g Inulin three times per day) for 3 months. Evaluation of treatment was done one month after the end of therapy. Seventy one children out of 110 (64.5%) had digestive symptoms in their medical history. The main signs were recurrent abdominal pain in 64 cases. BMI were less than 18.50 in all the children with H. pylori infection without other nutritional abnormaly. Eight children were eradicated after treatment
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Ndiaye, M F;
Mbengue, M;
Mbaye, P S;
Diouf, S;
[1]
Ghoos, Y;
[2]
Brunser, O
[3]
- Societe Senegalaise de Gasto-enterologie et d'hepatologie, Dakar (Senegal)
- Labo. Digestie Absorptie, Leuven (Belgium)
- Institute of Nutrition and Food Technology, Santiago (Chile)
Citation Formats
Ndiaye, M F, Mbengue, M, Mbaye, P S, Diouf, S, Ghoos, Y, and Brunser, O.
Treatment of children with Helicobacter pylori infection and malabsorption syndrome with probiotics: Comparison with conventional method.
IAEA: N. p.,
2004.
Web.
Ndiaye, M F, Mbengue, M, Mbaye, P S, Diouf, S, Ghoos, Y, & Brunser, O.
Treatment of children with Helicobacter pylori infection and malabsorption syndrome with probiotics: Comparison with conventional method.
IAEA.
Ndiaye, M F, Mbengue, M, Mbaye, P S, Diouf, S, Ghoos, Y, and Brunser, O.
2004.
"Treatment of children with Helicobacter pylori infection and malabsorption syndrome with probiotics: Comparison with conventional method."
IAEA.
@misc{etde_20507670,
title = {Treatment of children with Helicobacter pylori infection and malabsorption syndrome with probiotics: Comparison with conventional method}
author = {Ndiaye, M F, Mbengue, M, Mbaye, P S, Diouf, S, Ghoos, Y, and Brunser, O}
abstractNote = {Helicobacter pylori infection is one of the most common bacterial infection (82 %) in Senegal where malnutrition is common in children (25 %). Our aims were to definite prevalence of H. pylori, to determine the relationship between Hp infection and undernourishment and to verify the efficiency of treatment with probiotic. In some studies a positive effect of Saccharomyces boulardii has been demonstrated against H. pylori. We have included healthy children 7 to 10 years of age. 108 out of 129 (84%) were H. pylori-positive by breath-test. Two groups were randomised. Group A was treated with ten days' standard triple therapy (Omeprazole 1 mg Kg/day in single day gift, Amoxycillin 50 mg/kg/two times per day and Clarithromycin 250 mg two times per day). Group B received probiotic (250 mg of Saccharomyces boulardii with 5g Inulin three times per day) for 3 months. Evaluation of treatment was done one month after the end of therapy. Seventy one children out of 110 (64.5%) had digestive symptoms in their medical history. The main signs were recurrent abdominal pain in 64 cases. BMI were less than 18.50 in all the children with H. pylori infection without other nutritional abnormaly. Eight children were eradicated after treatment seven in the group under conventional treatment (58%) and one in the group under probiotics (6%). We concluded that prevalence of H. pylori infection is very high in young children as of the 7 years' age in urban as in rural environments. Symptoms are not specific. No significant difference in the nutritional state is observed between H. pylori-positive and H. pylori-negative children. Treatment by probiotics does not seem to give efficient results for eradication of H. pylori. (author)}
place = {IAEA}
year = {2004}
month = {Jul}
}
title = {Treatment of children with Helicobacter pylori infection and malabsorption syndrome with probiotics: Comparison with conventional method}
author = {Ndiaye, M F, Mbengue, M, Mbaye, P S, Diouf, S, Ghoos, Y, and Brunser, O}
abstractNote = {Helicobacter pylori infection is one of the most common bacterial infection (82 %) in Senegal where malnutrition is common in children (25 %). Our aims were to definite prevalence of H. pylori, to determine the relationship between Hp infection and undernourishment and to verify the efficiency of treatment with probiotic. In some studies a positive effect of Saccharomyces boulardii has been demonstrated against H. pylori. We have included healthy children 7 to 10 years of age. 108 out of 129 (84%) were H. pylori-positive by breath-test. Two groups were randomised. Group A was treated with ten days' standard triple therapy (Omeprazole 1 mg Kg/day in single day gift, Amoxycillin 50 mg/kg/two times per day and Clarithromycin 250 mg two times per day). Group B received probiotic (250 mg of Saccharomyces boulardii with 5g Inulin three times per day) for 3 months. Evaluation of treatment was done one month after the end of therapy. Seventy one children out of 110 (64.5%) had digestive symptoms in their medical history. The main signs were recurrent abdominal pain in 64 cases. BMI were less than 18.50 in all the children with H. pylori infection without other nutritional abnormaly. Eight children were eradicated after treatment seven in the group under conventional treatment (58%) and one in the group under probiotics (6%). We concluded that prevalence of H. pylori infection is very high in young children as of the 7 years' age in urban as in rural environments. Symptoms are not specific. No significant difference in the nutritional state is observed between H. pylori-positive and H. pylori-negative children. Treatment by probiotics does not seem to give efficient results for eradication of H. pylori. (author)}
place = {IAEA}
year = {2004}
month = {Jul}
}