Abstract
Helicobacter pylori has been recognized as a major etiologic factor in the development of chronic gastritis and peptic ulcer disease in adults and children. The infection has been linked to the development of gastric cancer, and in 1994 was classified as a group 1 carcinogen by the International Agency for Research on Cancer. The prevalence of H. pylori infection is inversely correlated to the socio-economic development and to unsatisfactory prevailing sanitary conditions. In developing countries, up to 90% of the adult population is colonized with this agent. In contrast, its prevalence in developed countries is lower, ranging from 25 to 50%. H. pylori colonization has been considered a public health problem, since its highest incidence occurs during the first few years of life, when children are growing and developing rapidly. The acquisition of the infection occurs mainly in early childhood, especially in developing countries, but the age at which it is acquired remains unknown. Infection with H. pylori during early infancy could be the initial step of a reaction which facilitates enteric infection in childhood leading to recurrent diarrhoea, malnutrition and growth failure. Micronutrient deficiencies resulting from these conditions may in turn facilitate malnutrition, immunological dysfunction and the persistence of
More>>
Citation Formats
None.
Co-ordinated research project on use of isotopic techniques to examine the significance of infection and other insults in early childhood to diarrhoea morbidity, mal-assimilation and failure to thrive. Report on the final research co-ordination meeting.
IAEA: N. p.,
2004.
Web.
None.
Co-ordinated research project on use of isotopic techniques to examine the significance of infection and other insults in early childhood to diarrhoea morbidity, mal-assimilation and failure to thrive. Report on the final research co-ordination meeting.
IAEA.
None.
2004.
"Co-ordinated research project on use of isotopic techniques to examine the significance of infection and other insults in early childhood to diarrhoea morbidity, mal-assimilation and failure to thrive. Report on the final research co-ordination meeting."
IAEA.
@misc{etde_20507661,
title = {Co-ordinated research project on use of isotopic techniques to examine the significance of infection and other insults in early childhood to diarrhoea morbidity, mal-assimilation and failure to thrive. Report on the final research co-ordination meeting}
author = {None}
abstractNote = {Helicobacter pylori has been recognized as a major etiologic factor in the development of chronic gastritis and peptic ulcer disease in adults and children. The infection has been linked to the development of gastric cancer, and in 1994 was classified as a group 1 carcinogen by the International Agency for Research on Cancer. The prevalence of H. pylori infection is inversely correlated to the socio-economic development and to unsatisfactory prevailing sanitary conditions. In developing countries, up to 90% of the adult population is colonized with this agent. In contrast, its prevalence in developed countries is lower, ranging from 25 to 50%. H. pylori colonization has been considered a public health problem, since its highest incidence occurs during the first few years of life, when children are growing and developing rapidly. The acquisition of the infection occurs mainly in early childhood, especially in developing countries, but the age at which it is acquired remains unknown. Infection with H. pylori during early infancy could be the initial step of a reaction which facilitates enteric infection in childhood leading to recurrent diarrhoea, malnutrition and growth failure. Micronutrient deficiencies resulting from these conditions may in turn facilitate malnutrition, immunological dysfunction and the persistence of infection. The {sup 13}C-urea breath test ({sup 13}C-UBT), which has been used extensively in developed countries, is a technique that is non invasive, reliable, comparatively cheap and without risk to patients. It is also convenient for use in field-based settings; it is currently considered the 'gold standard' against which all other techniques are compared. The International Atomic Energy Agency (IAEA), initiated the current Coordinated Research Project (CRP) with the principal objective of promoting the use of the {sup 13}C-urea breath test technique in the participating countries to study the prevalence of Helicobacter pylori and its impact on health and nutritional status of the children. The participating countries in this CRP were Argentina, Benin, Chile, India, Indonesia, Mexico, Pakistan and Senegal. All of these countries are undergoing developmental transition with changes in their socio-economic status that may introduce changes in the pattern of H. pylori colonization along time. Results of the studies conducted by the participating countries using the {sup 13}C-urea breath test were presented and discussed during this final Research Coordination Meeting (RCM)}
place = {IAEA}
year = {2004}
month = {Jul}
}
title = {Co-ordinated research project on use of isotopic techniques to examine the significance of infection and other insults in early childhood to diarrhoea morbidity, mal-assimilation and failure to thrive. Report on the final research co-ordination meeting}
author = {None}
abstractNote = {Helicobacter pylori has been recognized as a major etiologic factor in the development of chronic gastritis and peptic ulcer disease in adults and children. The infection has been linked to the development of gastric cancer, and in 1994 was classified as a group 1 carcinogen by the International Agency for Research on Cancer. The prevalence of H. pylori infection is inversely correlated to the socio-economic development and to unsatisfactory prevailing sanitary conditions. In developing countries, up to 90% of the adult population is colonized with this agent. In contrast, its prevalence in developed countries is lower, ranging from 25 to 50%. H. pylori colonization has been considered a public health problem, since its highest incidence occurs during the first few years of life, when children are growing and developing rapidly. The acquisition of the infection occurs mainly in early childhood, especially in developing countries, but the age at which it is acquired remains unknown. Infection with H. pylori during early infancy could be the initial step of a reaction which facilitates enteric infection in childhood leading to recurrent diarrhoea, malnutrition and growth failure. Micronutrient deficiencies resulting from these conditions may in turn facilitate malnutrition, immunological dysfunction and the persistence of infection. The {sup 13}C-urea breath test ({sup 13}C-UBT), which has been used extensively in developed countries, is a technique that is non invasive, reliable, comparatively cheap and without risk to patients. It is also convenient for use in field-based settings; it is currently considered the 'gold standard' against which all other techniques are compared. The International Atomic Energy Agency (IAEA), initiated the current Coordinated Research Project (CRP) with the principal objective of promoting the use of the {sup 13}C-urea breath test technique in the participating countries to study the prevalence of Helicobacter pylori and its impact on health and nutritional status of the children. The participating countries in this CRP were Argentina, Benin, Chile, India, Indonesia, Mexico, Pakistan and Senegal. All of these countries are undergoing developmental transition with changes in their socio-economic status that may introduce changes in the pattern of H. pylori colonization along time. Results of the studies conducted by the participating countries using the {sup 13}C-urea breath test were presented and discussed during this final Research Coordination Meeting (RCM)}
place = {IAEA}
year = {2004}
month = {Jul}
}