You need JavaScript to view this

Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels

Abstract

Background: Obesity, type 2 diabetes and cardiovascular disease (CVD) are a major concern in many parts of the world. In Northern Mexico, these problems have been reported to be higher the in the rest of the country. Objective: To assess the different risk factors based on body status (body composition, body size, fat distribution) and lifestyle factors (diet and physical activity) for the development of type 2 diabetes and CVD in men and women from different socio-economic levels in north-west Mexico. Methods: Non probabilistic sample selection by invitation was used to recruit subjects, completing quotas by age groups, gender and socio-economic status. The study included 350 men and women, 20-84 years pertaining to low and high income groups from the city of Hermosillo, Sonora, Mexico. All subjects were measured for body weight, height, waist and hip circumferences, skinfolds, bioimpedance analysis (BIA), systolic and diastolic blood pressure SBP, DBP). Body mass index (BMI) and waist to hip ratio were calculated. An oral glucose tolerance test (OGTT) after a 12 hour fast was performed and blood samples were taken for analysis of insulin, leptin, total cholesterol, HDL, LDL-cholesterol and serum triglycerides. In 273 of the 350 subjects physical activity was studied by  More>>
Authors:
Valencia Juillerat, M E; Gallegos, A C; Ballesteros, M N [1] 
  1. Centro de Investigacion en Alimentacion y Desarrollo, Sonora (Mexico); and others
Publication Date:
Jul 01, 2002
Product Type:
Conference
Report Number:
NAHRES-70
Resource Relation:
Conference: 2. research co-ordination meeting on application of nuclear techniques in the prevention of degenerative diseases (obesity and non-insulin dependent diseases) in ageing, Kingston (Jamaica), 25-29 Jun 2001; Other Information: 36 ref, 5 tabs, 5 figs; PBD: 2002; Related Information: In: Co-ordinated research project on application of nuclear techniques in the prevention of degenerative diseases (obesity and non-Insulin dependent diseases) in ageing. Report on the second research co-ordination meeting, 214 pages.
Subject:
60 APPLIED LIFE SCIENCES; ADULTS; BLOOD; BODY; BODY COMPOSITION; CARDIOVASCULAR DISEASES; CHOLESTEROL; DEUTERIUM; FATS; GLUCOSE; HIGH INCOME GROUPS; INSULIN; ISOTOPE DILUTION; LEPTIN; METABOLIC DISEASES; TRIGLYCERIDES
OSTI ID:
20487948
Research Organizations:
International Atomic Energy Agency, Section of Nutritional and Health-Related Environmental Studies, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
TRN: XA0404149061046
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
page(s) 123-142
Announcement Date:

Citation Formats

Valencia Juillerat, M E, Gallegos, A C, and Ballesteros, M N. Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels. IAEA: N. p., 2002. Web.
Valencia Juillerat, M E, Gallegos, A C, & Ballesteros, M N. Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels. IAEA.
Valencia Juillerat, M E, Gallegos, A C, and Ballesteros, M N. 2002. "Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels." IAEA.
@misc{etde_20487948,
title = {Risk factors for type 2 diabetes and cardiovascular disease in Mexican adults from different socio-economic levels}
author = {Valencia Juillerat, M E, Gallegos, A C, and Ballesteros, M N}
abstractNote = {Background: Obesity, type 2 diabetes and cardiovascular disease (CVD) are a major concern in many parts of the world. In Northern Mexico, these problems have been reported to be higher the in the rest of the country. Objective: To assess the different risk factors based on body status (body composition, body size, fat distribution) and lifestyle factors (diet and physical activity) for the development of type 2 diabetes and CVD in men and women from different socio-economic levels in north-west Mexico. Methods: Non probabilistic sample selection by invitation was used to recruit subjects, completing quotas by age groups, gender and socio-economic status. The study included 350 men and women, 20-84 years pertaining to low and high income groups from the city of Hermosillo, Sonora, Mexico. All subjects were measured for body weight, height, waist and hip circumferences, skinfolds, bioimpedance analysis (BIA), systolic and diastolic blood pressure SBP, DBP). Body mass index (BMI) and waist to hip ratio were calculated. An oral glucose tolerance test (OGTT) after a 12 hour fast was performed and blood samples were taken for analysis of insulin, leptin, total cholesterol, HDL, LDL-cholesterol and serum triglycerides. In 273 of the 350 subjects physical activity was studied by questionnaire. Activity was calculated as in categories of low, medium and high intensity and expressed as hours/day with respect to occupational and recreational activities. Physical activity level (PAL) was also calculated from the questionnaires. Body composition was investigated in more detail by air displacement plethysmography (densitometry) and by deuterium dilution in 200 subjects. Diet by 24 hour non-consecutive recalls in another sub-group of 135 male and female subjects. Statistical analysis was performed using NCSS statistical software using ANCOVA and regression procedures. Result: High levels of overweight (BMI >25) and obesity BMI>30) were found in this population group with 65 and 23.4% of them being in these categories respectively. After adjusting for sex and age, results showed that subjects with abnormal glucose tolerance levels had significantly higher weight (p<0.0001), BMI (p<0.0001), waist/hip ratio (p<0.0001), % body fat by BIA (p<0.0001), and systolic and diastolic blood pressure (p<0.0001), than normal subjects. Serum triglycerides and 2 hour glucose levels were significantly higher (p<0.0001) in subjects with overweight and central adiposity than in subjects with overweight only. The inverse was observed in the case of HDL-cholesterol levels (p<0.0001). Levels of obesity and overweight in this region are similar to those reported in developed countries. Of the anthropometric measurements, waist, waist/hip ratio and BMI showed the best correlation with respect to glycaemic status, blood lipids and insulin sensitivity ISI {sub 0,120}. In terms of body composition percent body fat by BL4 showed the best relationship to insulin sensitivity with the same index. Conclusions: Total body fat and regional fat distribution rather than body size may be a better alternative to assess risk levels for Type 2 diabetes and CVD. For population studies, this has to rely on appropriate field methods such as BIA. However, this has to be validated by recognised methodology such as deuterium dilution, DEXA or body density determinations that can provide the necessary information for specific predictive equation development. Work in Progress: Body composition by deuterium dilution determined by IR spectroscopy and plethysmography to validate BL4 are still in progress bt preliminary results show that either method can be used for validation purposes. Diet and physical activity data analysis will be completed by recruiting 50 mores subjects. Further analysis combining all possible risk indicators through multiple regression procedures are still pending as well as HOAL4 calculations. Take Home Message: The anthropometric evaluation of regional fat distribution and total body fat by BL4 might be an important field technique for type 2 diabetes and C VD risk assessment. Intervention studies that may use the findings in this study for this population would be warranted. (author)}
place = {IAEA}
year = {2002}
month = {Jul}
}