Abstract
We evaluated chronological changes of cerebral hemodynamics and metabolism of four focal brain injured (FBI) patients and four diffuse brain injured (DBI) patients in the chronic stage. We used positron emission tomography (PET) and compared the difference of the mechanism of recovery from neuronal damage between the two groups of subjects. The Glasgow Coma Scale score on admission was 6 to 14 in the FBI patients and 3 or 4 in the DBI patients. In the PET studies we examined regional cerebral blood flow (rCBF) and regional cerebral metabolic rate for oxygen (rCMRO{sub 2}) in gray matter. We conclude from our observations that rCBF and rCMRO{sub 2} values were strikingly different between the lesion area and the remote area in FBI patients, but were very similar in every area of the cerebral gray matter in the group of DBI patients. PET showed a poor recovery pattern in the surrounding area of the contusion in FBI patients. However, it showed an improvement of the rCBF and rCMRO{sub 2} values in every area of the DBI patients whose clinical condition had improved. In areas remote from the contusion in FBI patients, the pattern of improvement of the PET values was very similar
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Yamaki, Tarumi;
Tenjin, Hiroshi;
Imahori, Yoshio;
Ohmori, Yoshio;
Yoshino, Eiji;
Ueda, Satoshi;
[1]
Fujimoto, Masahito;
Sakakibara, Takehiko;
Mori, Toshiki
- Kyoto Prefectural Univ. of Medicine (Japan)
Citation Formats
Yamaki, Tarumi, Tenjin, Hiroshi, Imahori, Yoshio, Ohmori, Yoshio, Yoshino, Eiji, Ueda, Satoshi, Fujimoto, Masahito, Sakakibara, Takehiko, and Mori, Toshiki.
Difference of cerebral hemodynamics and metabolism between traumatic focal brain injury and diffuse brain injury in recovery process. Positron emission tomographic evaluation.
Japan: N. p.,
1995.
Web.
Yamaki, Tarumi, Tenjin, Hiroshi, Imahori, Yoshio, Ohmori, Yoshio, Yoshino, Eiji, Ueda, Satoshi, Fujimoto, Masahito, Sakakibara, Takehiko, & Mori, Toshiki.
Difference of cerebral hemodynamics and metabolism between traumatic focal brain injury and diffuse brain injury in recovery process. Positron emission tomographic evaluation.
Japan.
Yamaki, Tarumi, Tenjin, Hiroshi, Imahori, Yoshio, Ohmori, Yoshio, Yoshino, Eiji, Ueda, Satoshi, Fujimoto, Masahito, Sakakibara, Takehiko, and Mori, Toshiki.
1995.
"Difference of cerebral hemodynamics and metabolism between traumatic focal brain injury and diffuse brain injury in recovery process. Positron emission tomographic evaluation."
Japan.
@misc{etde_204817,
title = {Difference of cerebral hemodynamics and metabolism between traumatic focal brain injury and diffuse brain injury in recovery process. Positron emission tomographic evaluation}
author = {Yamaki, Tarumi, Tenjin, Hiroshi, Imahori, Yoshio, Ohmori, Yoshio, Yoshino, Eiji, Ueda, Satoshi, Fujimoto, Masahito, Sakakibara, Takehiko, and Mori, Toshiki}
abstractNote = {We evaluated chronological changes of cerebral hemodynamics and metabolism of four focal brain injured (FBI) patients and four diffuse brain injured (DBI) patients in the chronic stage. We used positron emission tomography (PET) and compared the difference of the mechanism of recovery from neuronal damage between the two groups of subjects. The Glasgow Coma Scale score on admission was 6 to 14 in the FBI patients and 3 or 4 in the DBI patients. In the PET studies we examined regional cerebral blood flow (rCBF) and regional cerebral metabolic rate for oxygen (rCMRO{sub 2}) in gray matter. We conclude from our observations that rCBF and rCMRO{sub 2} values were strikingly different between the lesion area and the remote area in FBI patients, but were very similar in every area of the cerebral gray matter in the group of DBI patients. PET showed a poor recovery pattern in the surrounding area of the contusion in FBI patients. However, it showed an improvement of the rCBF and rCMRO{sub 2} values in every area of the DBI patients whose clinical condition had improved. In areas remote from the contusion in FBI patients, the pattern of improvement of the PET values was very similar to that of DBI patients. This finding suggests that patients with FBI had some neuronal damage that was similar to that of DBI patients in remote areas from the contusion. The mechanism concerning the clinical improvement of the DBI patients is considered to involve axonal synaptic plasticity and the degree of clinical improvement to be strongly dependent on the degree of brain stem damage. (author).}
journal = []
issue = {2}
volume = {17}
journal type = {AC}
place = {Japan}
year = {1995}
month = {Jun}
}
title = {Difference of cerebral hemodynamics and metabolism between traumatic focal brain injury and diffuse brain injury in recovery process. Positron emission tomographic evaluation}
author = {Yamaki, Tarumi, Tenjin, Hiroshi, Imahori, Yoshio, Ohmori, Yoshio, Yoshino, Eiji, Ueda, Satoshi, Fujimoto, Masahito, Sakakibara, Takehiko, and Mori, Toshiki}
abstractNote = {We evaluated chronological changes of cerebral hemodynamics and metabolism of four focal brain injured (FBI) patients and four diffuse brain injured (DBI) patients in the chronic stage. We used positron emission tomography (PET) and compared the difference of the mechanism of recovery from neuronal damage between the two groups of subjects. The Glasgow Coma Scale score on admission was 6 to 14 in the FBI patients and 3 or 4 in the DBI patients. In the PET studies we examined regional cerebral blood flow (rCBF) and regional cerebral metabolic rate for oxygen (rCMRO{sub 2}) in gray matter. We conclude from our observations that rCBF and rCMRO{sub 2} values were strikingly different between the lesion area and the remote area in FBI patients, but were very similar in every area of the cerebral gray matter in the group of DBI patients. PET showed a poor recovery pattern in the surrounding area of the contusion in FBI patients. However, it showed an improvement of the rCBF and rCMRO{sub 2} values in every area of the DBI patients whose clinical condition had improved. In areas remote from the contusion in FBI patients, the pattern of improvement of the PET values was very similar to that of DBI patients. This finding suggests that patients with FBI had some neuronal damage that was similar to that of DBI patients in remote areas from the contusion. The mechanism concerning the clinical improvement of the DBI patients is considered to involve axonal synaptic plasticity and the degree of clinical improvement to be strongly dependent on the degree of brain stem damage. (author).}
journal = []
issue = {2}
volume = {17}
journal type = {AC}
place = {Japan}
year = {1995}
month = {Jun}
}