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ETDEWEB   /       /    Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL)

Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL)

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Abstract

After synthesis of fluorine-18 labelled analogues [{sup 18}F]fluorobenzoylation at the {alpha}-amino group, biodistribution and elimination of individual advanced glycation end products, namely N{sup {epsilon}}-carboxymethyllysine and N{sup {epsilon}}-carboxyethyllysine, was studied in comparison to lysine in rats after intravenous injection using positron emission tomography. (orig.)
Authors:
Bergmann, R; Helling, R; Henle, T; [1]  Heichert, C; Scheunemann, M; Maeding, P; Wittrisch, H; Johannsen, B
  1. Inst. of Food Chemistry, TU Dresden (Germany)
Publication Date:
Jan 01, 2002
Product Type:
Technical Report
Report Number:
FZR-340
Resource Relation:
Other Information: PBD: Jan 2002; Related Information: In: Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 2001, by Johannsen, B.; Seifert, S. (eds.), 109 pages.
Subject:
60 APPLIED LIFE SCIENCES; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; FLUORINE 18; LABELLED COMPOUNDS; TRACER TECHNIQUES; RATS; TISSUE DISTRIBUTION; SYNTHESIS; POSITRON COMPUTED TOMOGRAPHY; LYSINE; EXCRETION
OSTI ID:
20479602
Research Organizations:
Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Other: ISSN 1437-322X; TRN: DE04F7155
Availability:
INIS
Submitting Site:
DEN
Size:
page(s) 43
Announcement Date:
Jul 26, 2004

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Citation Formats

Bergmann, R, Helling, R, Henle, T, Heichert, C, Scheunemann, M, Maeding, P, Wittrisch, H, and Johannsen, B. Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL). Germany: N. p., 2002. Web.
Bergmann, R, Helling, R, Henle, T, Heichert, C, Scheunemann, M, Maeding, P, Wittrisch, H, & Johannsen, B. Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL). Germany.
Bergmann, R, Helling, R, Henle, T, Heichert, C, Scheunemann, M, Maeding, P, Wittrisch, H, and Johannsen, B. 2002. "Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL)." Germany.
@misc{etde_20479602,
title = {Biodistribution of the {sup 18}F-labelled advanced glycation end products N{sup {epsilon}}-carboxymethyllysine (CML) and N{sup {epsilon}}-carboxyethyllysine (CEL)}
 author = {Bergmann, R, Helling, R, Henle, T, Heichert, C, Scheunemann, M, Maeding, P, Wittrisch, H, and Johannsen, B}
 abstractNote = {After synthesis of fluorine-18 labelled analogues [{sup 18}F]fluorobenzoylation at the {alpha}-amino group, biodistribution and elimination of individual advanced glycation end products, namely N{sup {epsilon}}-carboxymethyllysine and N{sup {epsilon}}-carboxyethyllysine, was studied in comparison to lysine in rats after intravenous injection using positron emission tomography. (orig.)}
 place = {Germany}
 year = {2002}
 month = {Jan}
 }