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Medical imaging and chemistry; La chimie au service de l'imagerie medicale

Abstract

Diagnostic imaging frequently requires the use of agents that do not show an obvious role to patients. Nevertheless, these products fall definitely in the drug category and therefore are bound to the same development constraints, although no therapeutic effects are expected. This article attempts to explain the physical background of the most common imaging technologies as well as the mechanisms of action of the administered products. With these substances it is now possible to get morphological information with techniques based on X-rays, magnetic resonance or ultrasound, but also to obtain information on the functions of organs or cells by using radiolabeled molecules. Progresses, perspectives and limits of these technologies are described through several concrete examples. This overview demonstrates also that imaging participates strongly to the development of medicine. Diagnostics benefit simultaneously from technology improvements and new pharmaceuticals. (author)
Authors:
Meunier, J P; [1]  Schorsch, G; [2]  Zimmermann, R [3] 
  1. Schering France, Imagerie Medicale, 59 - Lys Les Lannoy (France)
  2. Actualite Chimique, 75 - Paris (France)
  3. Cis Bio International-Schering, Dir. Recherche et Developpement, 91 - Gif sur Yvette (France)
Publication Date:
Dec 01, 2003
Product Type:
Journal Article
Resource Relation:
Journal Name: Actualite Chimique; Journal Issue: 11-12; Other Information: PBD: Nov-Dec 2003
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CONTRAST MEDIA; IMAGE PROCESSING; IMAGES; MEDICAL EXAMINATIONS; NMR IMAGING; NUCLEAR MEDICINE; RADIOPHARMACEUTICALS; SCINTISCANNING; TOMOGRAPHY; ULTRASONOGRAPHY; X RADIATION
OSTI ID:
20476988
Country of Origin:
France
Language:
French
Other Identifying Numbers:
Journal ID: ISSN 0151-9093; ACCHDG; TRN: FR0400395051085
Submitting Site:
FRN
Size:
page(s) 49-56
Announcement Date:
Jul 20, 2004

Citation Formats

Meunier, J P, Schorsch, G, and Zimmermann, R. Medical imaging and chemistry; La chimie au service de l'imagerie medicale. France: N. p., 2003. Web.
Meunier, J P, Schorsch, G, & Zimmermann, R. Medical imaging and chemistry; La chimie au service de l'imagerie medicale. France.
Meunier, J P, Schorsch, G, and Zimmermann, R. 2003. "Medical imaging and chemistry; La chimie au service de l'imagerie medicale." France.
@misc{etde_20476988,
title = {Medical imaging and chemistry; La chimie au service de l'imagerie medicale}
author = {Meunier, J P, Schorsch, G, and Zimmermann, R}
abstractNote = {Diagnostic imaging frequently requires the use of agents that do not show an obvious role to patients. Nevertheless, these products fall definitely in the drug category and therefore are bound to the same development constraints, although no therapeutic effects are expected. This article attempts to explain the physical background of the most common imaging technologies as well as the mechanisms of action of the administered products. With these substances it is now possible to get morphological information with techniques based on X-rays, magnetic resonance or ultrasound, but also to obtain information on the functions of organs or cells by using radiolabeled molecules. Progresses, perspectives and limits of these technologies are described through several concrete examples. This overview demonstrates also that imaging participates strongly to the development of medicine. Diagnostics benefit simultaneously from technology improvements and new pharmaceuticals. (author)}
journal = []
issue = {11-12}
journal type = {AC}
place = {France}
year = {2003}
month = {Dec}
}