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Use of Monte Carlo Methods for determination of isodose curves in brachytherapy; Uso de tecnicas Monte Carlo para determinacao de curvas de isodose em braquiterapia

Abstract

Brachytherapy is a special form of cancer treatment in which the radioactive source is very close to or inside the tumor with the objective of causing the necrosis of the cancerous tissue. The intensity of cell response to the radiation varies according to the tissue type and degree of differentiation. Since the malign cells are less differentiated than the normal ones, they are more sensitive to the radiation. This is the basis for radiotherapy techniques. Institutes that work with the application of high dose rates use sophisticated computer programs to calculate the necessary dose to achieve the necrosis of the tumor and the same time, minimizing the irradiation of tissues and organs of the neighborhood. With knowledge the characteristics of the source and the tumor, it is possible to trace isodose curves with the necessary information for planning the brachytherapy in patients. The objective of this work is, using Monte Carlo techniques, to develop a computer program - the ISODOSE - which allows to determine isodose curves in turn of linear radioactive sources used in brachytherapy. The development of ISODOSE is important because the available commercial programs, in general, are very expensive and practically inaccessible to small clinics. The use  More>>
Publication Date:
Aug 01, 2001
Product Type:
Thesis/Dissertation
Report Number:
INIS-BR-3861
Resource Relation:
Other Information: TH: Dissertacao (M.Sc.); 24 refs., 19 figs., 22 tabs; PBD: Aug 2001
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; ANIMAL TISSUES; COMPUTER CODES; CUMULATIVE RADIATION EFFECTS; DEPTH DOSE DISTRIBUTIONS; IRRADIATION; ISODOSE CURVES; MONTE CARLO METHOD; NECROSIS; NEOPLASMS; RADIOTHERAPY
OSTI ID:
20471964
Research Organizations:
Pernambuco Univ., Recife, PE (Brazil). Dept. de Energia Nuclear. Programa de Pos-graduacao em Tecnologias Energeticas e Nucleares
Country of Origin:
Brazil
Language:
Portuguese
Other Identifying Numbers:
TRN: BR0443959047096
Availability:
Available from INIS in electronic form
Submitting Site:
BRN
Size:
89 pages
Announcement Date:

Citation Formats

Vieira, Jose Wilson. Use of Monte Carlo Methods for determination of isodose curves in brachytherapy; Uso de tecnicas Monte Carlo para determinacao de curvas de isodose em braquiterapia. Brazil: N. p., 2001. Web.
Vieira, Jose Wilson. Use of Monte Carlo Methods for determination of isodose curves in brachytherapy; Uso de tecnicas Monte Carlo para determinacao de curvas de isodose em braquiterapia. Brazil.
Vieira, Jose Wilson. 2001. "Use of Monte Carlo Methods for determination of isodose curves in brachytherapy; Uso de tecnicas Monte Carlo para determinacao de curvas de isodose em braquiterapia." Brazil.
@misc{etde_20471964,
title = {Use of Monte Carlo Methods for determination of isodose curves in brachytherapy; Uso de tecnicas Monte Carlo para determinacao de curvas de isodose em braquiterapia}
author = {Vieira, Jose Wilson}
abstractNote = {Brachytherapy is a special form of cancer treatment in which the radioactive source is very close to or inside the tumor with the objective of causing the necrosis of the cancerous tissue. The intensity of cell response to the radiation varies according to the tissue type and degree of differentiation. Since the malign cells are less differentiated than the normal ones, they are more sensitive to the radiation. This is the basis for radiotherapy techniques. Institutes that work with the application of high dose rates use sophisticated computer programs to calculate the necessary dose to achieve the necrosis of the tumor and the same time, minimizing the irradiation of tissues and organs of the neighborhood. With knowledge the characteristics of the source and the tumor, it is possible to trace isodose curves with the necessary information for planning the brachytherapy in patients. The objective of this work is, using Monte Carlo techniques, to develop a computer program - the ISODOSE - which allows to determine isodose curves in turn of linear radioactive sources used in brachytherapy. The development of ISODOSE is important because the available commercial programs, in general, are very expensive and practically inaccessible to small clinics. The use of Monte Carlo techniques is viable because they avoid problems inherent to analytic solutions as, for instance , the integration of functions with singularities in its domain. The results of ISODOSE were compared with similar data found in the literature and also with those obtained at the institutes of radiotherapy of the 'Hospital do Cancer do Recife' and of the 'Hospital Portugues do Recife'. ISODOSE presented good performance, mainly, due to the Monte Carlo techniques, that allowed a quite detailed drawing of the isodose curves in turn of linear sources. (author)}
place = {Brazil}
year = {2001}
month = {Aug}
}