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MR imaging of renal cell carcinoma. Associations among signal intensity, tumor enhancement, and pathologic findings

Journal Article:

Abstract

The purpose of this study was to compare the MR characteristics of renal cell carcinomas against histologic findings and to assess the correlations among signal intensity, tumor enhancement, and pathologic findings. Fifty-four patients (56 lesions) were examined by MR imaging and then underwent partial or radical nephrectomy. The pathologic diagnosis of all lesions was renal cell carcinoma. All MR examinations were performed as dynamic studies using the same 1.5-T scanner. MR characteristics were compared against pathologic findings after resection, and the correlations among signal intensity, tumor enhancement, and pathologic findings were then assessed. A significant correlation was observed between tumor grade and tumor enhancement, with G3 lesions tending to show little enhancement. Regardless of the histologic classification, G3 tumors were found to contain highly heterotypic cancer cells and very few vessels by histopathologic examination. No significant correlations were noted between the other MR characteristics and pathologic findings. Renal cell carcinomas showing little enhancement tend to be highly malignant lesions based on the pathologic findings. Special consideration is required for these tumors with regard to the selection of surgical intervention and follow-up observation. (author)
Authors:
Yabuki, Takayuki; Togami, Izumi; Kitagawa, Takahiro; Sasai, Nobuya; Tsushima, Tomoyasu; Shirasaki, Yoshinori; Hiraki, Yoshio [1] 
  1. Okayama Univ. (Japan). Graduate School of Medicine and Dentistry
Publication Date:
Aug 01, 2003
Product Type:
Journal Article
Resource Relation:
Journal Name: Acta Medica Okayama; Journal Volume: 57; Journal Issue: 4; Other Information: PBD: Aug 2003
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; COMPARATIVE EVALUATIONS; DTPA; GADOLINIUM COMPLEXES; HISTOLOGY; KIDNEYS; NMR IMAGING; SIGNALS; SPIN-LATTICE RELAXATION; SPIN-SPIN RELAXATION
OSTI ID:
20411283
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0386-300X; AMOKAG; TRN: JP0304393085016
Submitting Site:
INIS
Size:
page(s) 179-186
Announcement Date:

Journal Article:

Citation Formats

Yabuki, Takayuki, Togami, Izumi, Kitagawa, Takahiro, Sasai, Nobuya, Tsushima, Tomoyasu, Shirasaki, Yoshinori, and Hiraki, Yoshio. MR imaging of renal cell carcinoma. Associations among signal intensity, tumor enhancement, and pathologic findings. Japan: N. p., 2003. Web.
Yabuki, Takayuki, Togami, Izumi, Kitagawa, Takahiro, Sasai, Nobuya, Tsushima, Tomoyasu, Shirasaki, Yoshinori, & Hiraki, Yoshio. MR imaging of renal cell carcinoma. Associations among signal intensity, tumor enhancement, and pathologic findings. Japan.
Yabuki, Takayuki, Togami, Izumi, Kitagawa, Takahiro, Sasai, Nobuya, Tsushima, Tomoyasu, Shirasaki, Yoshinori, and Hiraki, Yoshio. 2003. "MR imaging of renal cell carcinoma. Associations among signal intensity, tumor enhancement, and pathologic findings." Japan.
@misc{etde_20411283,
title = {MR imaging of renal cell carcinoma. Associations among signal intensity, tumor enhancement, and pathologic findings}
author = {Yabuki, Takayuki, Togami, Izumi, Kitagawa, Takahiro, Sasai, Nobuya, Tsushima, Tomoyasu, Shirasaki, Yoshinori, and Hiraki, Yoshio}
abstractNote = {The purpose of this study was to compare the MR characteristics of renal cell carcinomas against histologic findings and to assess the correlations among signal intensity, tumor enhancement, and pathologic findings. Fifty-four patients (56 lesions) were examined by MR imaging and then underwent partial or radical nephrectomy. The pathologic diagnosis of all lesions was renal cell carcinoma. All MR examinations were performed as dynamic studies using the same 1.5-T scanner. MR characteristics were compared against pathologic findings after resection, and the correlations among signal intensity, tumor enhancement, and pathologic findings were then assessed. A significant correlation was observed between tumor grade and tumor enhancement, with G3 lesions tending to show little enhancement. Regardless of the histologic classification, G3 tumors were found to contain highly heterotypic cancer cells and very few vessels by histopathologic examination. No significant correlations were noted between the other MR characteristics and pathologic findings. Renal cell carcinomas showing little enhancement tend to be highly malignant lesions based on the pathologic findings. Special consideration is required for these tumors with regard to the selection of surgical intervention and follow-up observation. (author)}
journal = {Acta Medica Okayama}
issue = {4}
volume = {57}
journal type = {AC}
place = {Japan}
year = {2003}
month = {Aug}
}