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'Fitesten' in treatment of postradiation syndrome; Pecradiacijas sindroma arstesanas rezultati ar fitestenu

Abstract

Investigation of 'Fitesten' (a complex of bioactive substances and vitamins from the pine and spruce needles) in therapy of postradiation syndrome was performed in 58 males 34-69 years old of whom took part during 1986 and 1990 in the elimination of the effects in the 30 km zone of the Chernobyl NPP breakdown. The methods of study was double blind randomised trial with placebo control. Patients underwent 30-day course of therapy with 'Fitesten' by 2 capsules (0,5 g) 3 times a day. Before and after treatment we found that the antioxidant ferments activity (glutationperoxidase in serum and erythrocytes, catalase in erythrocytes) and lipid peroxidation level of whole blood (hydroperoxids content, oxidability of plasma, oxidation rate). According to data obtained we may conclude that the before all indexes of the lipid peroxidation level were increased and pathological disorders to antioxidant ferment activity were founded. Treatment course with 'Fitesten' decreased in fatigue, influenced antioxidant effect (reduced lipid peroxidation level, modulating of catalase activity). Taking in attention all above-mentioned data we came to conclusion that the intake of preparation 'Fitesten' can supplement and optimise the therapy of patients with postradiation syndrome. (authors)
Authors:
Seleznovs, J; Orlikovs, G; Farbtuha, T; Kumerova, A; Skesters, A; Lece, A; Ponomarenko, J; Smirnova, K; Pokrotnieks, J [1] 
  1. Medical Academy of Latvia / Riga Stradins University, Riga (Latvia)
Publication Date:
Jul 01, 2001
Product Type:
Miscellaneous
Resource Relation:
Other Information: 26 refs., 2 tabs., 4 figs; PBD: 2001; Related Information: In: Internal medicine, Surgery, Basic sciences in medicine, Stomatology, Pharmacy. Scientific publications in medicine in year 2000, Interna medicina, Kirurgija, Medicinas bazes zinatnes, Stomatologija, Farmacija. 2000 gada medicinas nozares petnieciska darba publikacijas, Scientific Proceedings of Medical Academy of Latvia / Riga Stradins University, 200 pages.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; CHERNOBYLSK-4 REACTOR; DRUGS; MEDICAL SURVEILLANCE; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; POST-IRRADIATION THERAPY; REACTOR ACCIDENTS
OSTI ID:
20404642
Research Organizations:
Medical Academy of Latvia / Riga Stradins University, Riga (Latvia)
Country of Origin:
Latvia
Language:
English
Other Identifying Numbers:
Other: ISBN 9984-550-29-X; TRN: LV0300070079265
Submitting Site:
INIS
Size:
page(s) 53-56
Announcement Date:
Dec 15, 2003

Citation Formats

Seleznovs, J, Orlikovs, G, Farbtuha, T, Kumerova, A, Skesters, A, Lece, A, Ponomarenko, J, Smirnova, K, and Pokrotnieks, J. 'Fitesten' in treatment of postradiation syndrome; Pecradiacijas sindroma arstesanas rezultati ar fitestenu. Latvia: N. p., 2001. Web.
Seleznovs, J, Orlikovs, G, Farbtuha, T, Kumerova, A, Skesters, A, Lece, A, Ponomarenko, J, Smirnova, K, & Pokrotnieks, J. 'Fitesten' in treatment of postradiation syndrome; Pecradiacijas sindroma arstesanas rezultati ar fitestenu. Latvia.
Seleznovs, J, Orlikovs, G, Farbtuha, T, Kumerova, A, Skesters, A, Lece, A, Ponomarenko, J, Smirnova, K, and Pokrotnieks, J. 2001. "'Fitesten' in treatment of postradiation syndrome; Pecradiacijas sindroma arstesanas rezultati ar fitestenu." Latvia.
@misc{etde_20404642,
title = {'Fitesten' in treatment of postradiation syndrome; Pecradiacijas sindroma arstesanas rezultati ar fitestenu}
author = {Seleznovs, J, Orlikovs, G, Farbtuha, T, Kumerova, A, Skesters, A, Lece, A, Ponomarenko, J, Smirnova, K, and Pokrotnieks, J}
abstractNote = {Investigation of 'Fitesten' (a complex of bioactive substances and vitamins from the pine and spruce needles) in therapy of postradiation syndrome was performed in 58 males 34-69 years old of whom took part during 1986 and 1990 in the elimination of the effects in the 30 km zone of the Chernobyl NPP breakdown. The methods of study was double blind randomised trial with placebo control. Patients underwent 30-day course of therapy with 'Fitesten' by 2 capsules (0,5 g) 3 times a day. Before and after treatment we found that the antioxidant ferments activity (glutationperoxidase in serum and erythrocytes, catalase in erythrocytes) and lipid peroxidation level of whole blood (hydroperoxids content, oxidability of plasma, oxidation rate). According to data obtained we may conclude that the before all indexes of the lipid peroxidation level were increased and pathological disorders to antioxidant ferment activity were founded. Treatment course with 'Fitesten' decreased in fatigue, influenced antioxidant effect (reduced lipid peroxidation level, modulating of catalase activity). Taking in attention all above-mentioned data we came to conclusion that the intake of preparation 'Fitesten' can supplement and optimise the therapy of patients with postradiation syndrome. (authors)}
place = {Latvia}
year = {2001}
month = {Jul}
}