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Preliminary evaluation of intraoperative gamma probe detection of the sentinel node

Journal Article:

Abstract

Introduction: The resurgence of the lymphoscintigraphy with the sentinel node concept and the availability of the intraoperative gamma probe have been proposed to avoid the morbidity of an unnecessary regional node dissection. The aim of the study was to evaluate the intraoperative gamma probe use after lymphoscintigraphy for the localization of the sentinel node. Material and methods: Twenty-nine patients were studied, 18 females (62%), mean age 60 {+-} 19 y.o. (range 24-86 y.o.) at the Military Hospital Nuclear Medicine Department. The reference diagnoses were 66% malignant melanoma, 21 % breast cancer, 10 % head and neck cancer and 3% vulvae cancer. Lymphoscintigraphs were performed with Tc99m-Dextran injected intradermally in four points around the primary lesion or around the biopsy site (for melanoma 500 microCi each one; for breast and head and neck 200 microCi each one). Afterwards, dynamic images were taken, followed by intraoperative gamma probe investigations in order to localize and remove the sentinel node. Additionally, isosulfan blue was injected before the surgery was made. Results: Lymphoscintigraphy was positive to detect sentinel node(s) in 20 patients (69%). During the surgery, 40 sentinel nodes were detected. In 33 cases, the intraoperative gamma probe was performed, of which 88 % were  More>>
Authors:
Sierralta, M P; Jofre, M J; [1]  Iglesis, R; Schwartz, R; Gomez, L; Velez, R; [2]  Sandoval, R [3] 
  1. Nuclear Medicine Department, Military Hospital, Santiago (Chile)
  2. Surgery Department, Military Hospital, Santiago (Chile)
  3. Pathology Department, Military Hospital, Santiago (Chile)
Publication Date:
Sep 01, 2002
Product Type:
Journal Article
Resource Relation:
Journal Name: World Journal of Nuclear Medicine; Journal Volume: 1; Journal Issue: suppl.2; Conference: 8. Congress of the World Federation of Nuclear Medicine and Biology, Santiago (Chile), 29 Sep - 2 Oct 2002; Other Information: 1 tab; PBD: Sep 2002
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; GAMMA RADIATION; LYMPHATIC SYSTEM; NEOPLASMS; SCINTISCANNING; SURGERY
OSTI ID:
20365774
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1450-1147; TRN: XA03W0600048883
Submitting Site:
INIS
Size:
page(s) 271-272
Announcement Date:

Journal Article:

Citation Formats

Sierralta, M P, Jofre, M J, Iglesis, R, Schwartz, R, Gomez, L, Velez, R, and Sandoval, R. Preliminary evaluation of intraoperative gamma probe detection of the sentinel node. IAEA: N. p., 2002. Web.
Sierralta, M P, Jofre, M J, Iglesis, R, Schwartz, R, Gomez, L, Velez, R, & Sandoval, R. Preliminary evaluation of intraoperative gamma probe detection of the sentinel node. IAEA.
Sierralta, M P, Jofre, M J, Iglesis, R, Schwartz, R, Gomez, L, Velez, R, and Sandoval, R. 2002. "Preliminary evaluation of intraoperative gamma probe detection of the sentinel node." IAEA.
@misc{etde_20365774,
title = {Preliminary evaluation of intraoperative gamma probe detection of the sentinel node}
author = {Sierralta, M P, Jofre, M J, Iglesis, R, Schwartz, R, Gomez, L, Velez, R, and Sandoval, R}
abstractNote = {Introduction: The resurgence of the lymphoscintigraphy with the sentinel node concept and the availability of the intraoperative gamma probe have been proposed to avoid the morbidity of an unnecessary regional node dissection. The aim of the study was to evaluate the intraoperative gamma probe use after lymphoscintigraphy for the localization of the sentinel node. Material and methods: Twenty-nine patients were studied, 18 females (62%), mean age 60 {+-} 19 y.o. (range 24-86 y.o.) at the Military Hospital Nuclear Medicine Department. The reference diagnoses were 66% malignant melanoma, 21 % breast cancer, 10 % head and neck cancer and 3% vulvae cancer. Lymphoscintigraphs were performed with Tc99m-Dextran injected intradermally in four points around the primary lesion or around the biopsy site (for melanoma 500 microCi each one; for breast and head and neck 200 microCi each one). Afterwards, dynamic images were taken, followed by intraoperative gamma probe investigations in order to localize and remove the sentinel node. Additionally, isosulfan blue was injected before the surgery was made. Results: Lymphoscintigraphy was positive to detect sentinel node(s) in 20 patients (69%). During the surgery, 40 sentinel nodes were detected. In 33 cases, the intraoperative gamma probe was performed, of which 88 % were radioactives. In 35 nodes, the isosulfan blue was injected, of which 80 % were dyed. The correlation between both techniques was 75 %. The histology study of 37 samples demonstrated that 86% (n=32) were truly ganglionar nodes. Conclusion: The intraoperative gamma probe after lymphoscintigraphy is a useful technique for the localization of the sentinel node.}
journal = {World Journal of Nuclear Medicine}
issue = {suppl.2}
volume = {1}
journal type = {AC}
place = {IAEA}
year = {2002}
month = {Sep}
}