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Cellular response to low Gamma-ray doses

Abstract

Lymphocytes, obtained from healthy donors, were exposed to a low strength gamma-ray field to determine heat shock protein expression in function of radiation dose. Protein identification was carried out using mAb raised against Hsp70 and Hsc70.Hsp70 protein was detected after lymphocyte irradiation. In all cases, an increasing trend of relative amounts of Hsp70 in function to irradiation time was observed. After 1.25 c Gy gamma-ray dose, lymphocytes expressed Hsp70 protein, indicating a threshold response to gamma rays. (Author)
Authors:
Manzanares A, E; Vega C, H R; Leon, L.C. de .; [1]  Rebolledo D, O; Radillo J, F [2] 
  1. Unidades Academicas de Estudios Nucleares, Universidad Autonoma de Zacatecas, A.P. 336, 98000 Zacatecas (Mexico)
  2. Facultad de Ciencias Biologicas y Agropecuarias de la Universidad de Colima, Colima (Mexico)
Publication Date:
Jul 01, 2002
Product Type:
Conference
Report Number:
INIS-MX-1217
Resource Relation:
Conference: 5. International Conference. 15 National Congress on Solid State Dosimetry, Mexico City (Mexico), 11-13 Sep 2002; Other Information: PBD: 2002
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BLOOD; DIAGRAMS; GAMMA RADIATION; IMAGES; LYMPHOCYTES; MAN; PROTEINS; RADIATION DOSES; SAMPLING; SULFUR 35
OSTI ID:
20336896
Research Organizations:
Universidad Autonoma Metropolitana, Mexico D.F. Consejo Nacional de Ciencia y Tecnologia, CONACyT, Mexico D.F. (Mexico)
Country of Origin:
Mexico
Language:
English
Other Identifying Numbers:
Other: ISBN 03-2002-082709460100-01; TRN: MX0300131023868
Availability:
Available from INIS in electronic form
Submitting Site:
MXN
Size:
7 pages
Announcement Date:

Citation Formats

Manzanares A, E, Vega C, H R, Leon, L.C. de ., Rebolledo D, O, and Radillo J, F. Cellular response to low Gamma-ray doses. Mexico: N. p., 2002. Web.
Manzanares A, E, Vega C, H R, Leon, L.C. de ., Rebolledo D, O, & Radillo J, F. Cellular response to low Gamma-ray doses. Mexico.
Manzanares A, E, Vega C, H R, Leon, L.C. de ., Rebolledo D, O, and Radillo J, F. 2002. "Cellular response to low Gamma-ray doses." Mexico.
@misc{etde_20336896,
title = {Cellular response to low Gamma-ray doses}
author = {Manzanares A, E, Vega C, H R, Leon, L.C. de ., Rebolledo D, O, and Radillo J, F}
abstractNote = {Lymphocytes, obtained from healthy donors, were exposed to a low strength gamma-ray field to determine heat shock protein expression in function of radiation dose. Protein identification was carried out using mAb raised against Hsp70 and Hsc70.Hsp70 protein was detected after lymphocyte irradiation. In all cases, an increasing trend of relative amounts of Hsp70 in function to irradiation time was observed. After 1.25 c Gy gamma-ray dose, lymphocytes expressed Hsp70 protein, indicating a threshold response to gamma rays. (Author)}
place = {Mexico}
year = {2002}
month = {Jul}
}