Abstract
HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides was performed and the relationships between mutation frequency and dose were studied. Rats were injected intravenously with radionuclides, the blood was sampled at different time after injection; HPRT gene locus mutation frequency (GMF) were examined by methods of multi-nucleus cell and Brdurd assay, working out the Dose-response function. GMF rose with the increase of dose and dose-rates and were clearly interrelated. The HPRT gene locus mutation is very sensitive to radiation and may be used as a biological dosimeter.
Jingyong, Zhao;
Yongzhong, Xu;
Tao, Zhao;
Fengmei, Cui;
Liuyi, Wang;
Qinhua, Lao
[1]
- Suzhou Univ., Suzhou (China). Radiation Medicine Department
Citation Formats
Jingyong, Zhao, Yongzhong, Xu, Tao, Zhao, Fengmei, Cui, Liuyi, Wang, and Qinhua, Lao.
HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides.
China: N. p.,
2001.
Web.
Jingyong, Zhao, Yongzhong, Xu, Tao, Zhao, Fengmei, Cui, Liuyi, Wang, & Qinhua, Lao.
HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides.
China.
Jingyong, Zhao, Yongzhong, Xu, Tao, Zhao, Fengmei, Cui, Liuyi, Wang, and Qinhua, Lao.
2001.
"HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides."
China.
@misc{etde_20315874,
title = {HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides}
author = {Jingyong, Zhao, Yongzhong, Xu, Tao, Zhao, Fengmei, Cui, Liuyi, Wang, and Qinhua, Lao}
abstractNote = {HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides was performed and the relationships between mutation frequency and dose were studied. Rats were injected intravenously with radionuclides, the blood was sampled at different time after injection; HPRT gene locus mutation frequency (GMF) were examined by methods of multi-nucleus cell and Brdurd assay, working out the Dose-response function. GMF rose with the increase of dose and dose-rates and were clearly interrelated. The HPRT gene locus mutation is very sensitive to radiation and may be used as a biological dosimeter.}
place = {China}
year = {2001}
month = {Jul}
}
title = {HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides}
author = {Jingyong, Zhao, Yongzhong, Xu, Tao, Zhao, Fengmei, Cui, Liuyi, Wang, and Qinhua, Lao}
abstractNote = {HPRT gene locus mutation in peripheral blood lymphocytes induced by internal exposure to radionuclides was performed and the relationships between mutation frequency and dose were studied. Rats were injected intravenously with radionuclides, the blood was sampled at different time after injection; HPRT gene locus mutation frequency (GMF) were examined by methods of multi-nucleus cell and Brdurd assay, working out the Dose-response function. GMF rose with the increase of dose and dose-rates and were clearly interrelated. The HPRT gene locus mutation is very sensitive to radiation and may be used as a biological dosimeter.}
place = {China}
year = {2001}
month = {Jul}
}