Abstract
The modalities and the indications of perfusion and neurotransmission SPECT in childhood are presented. The perfusion as well as neurotransmission tracers have not yet authorization for use in children; they have to be used by prescription of magistral preparation or in research protocols. The radioprotection rules have to be strictly respected. The most frequent indication of perfusion SPECT is pharmacologically resistant epilepsy; the ictal SPECT before surgery allows the localization of the epileptogenic focus. Other indications are relevant in the prognosis of neonatal anoxia and encephalitis. In psychiatric disorders, especially in autism, the interest is the physiopathological approach of the brain dysfunctions. The neurotransmission SPECT is emerging as a consequence of the development of new radiotracer, as the dopaminergic system ligands. The decrease of the dopamine D2 receptors in the striatum can be imaged and quantified in the neonate. The lesions of dopamine system seem to be a consequence of the neonatal hypoxia-ischemia and it is predictive of motor sequelae. Brain SPECT should become a routine examination in child neurologic and psychiatric disorders. (authors)
Tranquart, F;
Saliba, E;
Prunier, C;
Baulieu, F;
Besnard, J C;
Guilloteau, D;
Baulieu, J L
[1]
- Hopital Bretonneau, Service de Medecine Nucleaire, Unite Inserm 316, 37 - Tours (France)
Citation Formats
Tranquart, F, Saliba, E, Prunier, C, Baulieu, F, Besnard, J C, Guilloteau, D, and Baulieu, J L.
Brain SPECT in childhood; Temp cerebrale chez l'enfant.
France: N. p.,
2001.
Web.
Tranquart, F, Saliba, E, Prunier, C, Baulieu, F, Besnard, J C, Guilloteau, D, & Baulieu, J L.
Brain SPECT in childhood; Temp cerebrale chez l'enfant.
France.
Tranquart, F, Saliba, E, Prunier, C, Baulieu, F, Besnard, J C, Guilloteau, D, and Baulieu, J L.
2001.
"Brain SPECT in childhood; Temp cerebrale chez l'enfant."
France.
@misc{etde_20200229,
title = {Brain SPECT in childhood; Temp cerebrale chez l'enfant}
author = {Tranquart, F, Saliba, E, Prunier, C, Baulieu, F, Besnard, J C, Guilloteau, D, and Baulieu, J L}
abstractNote = {The modalities and the indications of perfusion and neurotransmission SPECT in childhood are presented. The perfusion as well as neurotransmission tracers have not yet authorization for use in children; they have to be used by prescription of magistral preparation or in research protocols. The radioprotection rules have to be strictly respected. The most frequent indication of perfusion SPECT is pharmacologically resistant epilepsy; the ictal SPECT before surgery allows the localization of the epileptogenic focus. Other indications are relevant in the prognosis of neonatal anoxia and encephalitis. In psychiatric disorders, especially in autism, the interest is the physiopathological approach of the brain dysfunctions. The neurotransmission SPECT is emerging as a consequence of the development of new radiotracer, as the dopaminergic system ligands. The decrease of the dopamine D2 receptors in the striatum can be imaged and quantified in the neonate. The lesions of dopamine system seem to be a consequence of the neonatal hypoxia-ischemia and it is predictive of motor sequelae. Brain SPECT should become a routine examination in child neurologic and psychiatric disorders. (authors)}
journal = []
issue = {4}
volume = {25}
journal type = {AC}
place = {France}
year = {2001}
month = {Apr}
}
title = {Brain SPECT in childhood; Temp cerebrale chez l'enfant}
author = {Tranquart, F, Saliba, E, Prunier, C, Baulieu, F, Besnard, J C, Guilloteau, D, and Baulieu, J L}
abstractNote = {The modalities and the indications of perfusion and neurotransmission SPECT in childhood are presented. The perfusion as well as neurotransmission tracers have not yet authorization for use in children; they have to be used by prescription of magistral preparation or in research protocols. The radioprotection rules have to be strictly respected. The most frequent indication of perfusion SPECT is pharmacologically resistant epilepsy; the ictal SPECT before surgery allows the localization of the epileptogenic focus. Other indications are relevant in the prognosis of neonatal anoxia and encephalitis. In psychiatric disorders, especially in autism, the interest is the physiopathological approach of the brain dysfunctions. The neurotransmission SPECT is emerging as a consequence of the development of new radiotracer, as the dopaminergic system ligands. The decrease of the dopamine D2 receptors in the striatum can be imaged and quantified in the neonate. The lesions of dopamine system seem to be a consequence of the neonatal hypoxia-ischemia and it is predictive of motor sequelae. Brain SPECT should become a routine examination in child neurologic and psychiatric disorders. (authors)}
journal = []
issue = {4}
volume = {25}
journal type = {AC}
place = {France}
year = {2001}
month = {Apr}
}