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Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences

Abstract

The existing activities of the Department of Life Sciences have grown out of the specific know-how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know-how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development.  More>>
Authors:
Jaussi, Rolf; Gschwend, Beatrice [1] 
  1. eds.
Publication Date:
Jul 01, 2001
Product Type:
Technical Report
Report Number:
INIS-CH-032
Reference Number:
EDB-01:060791
Resource Relation:
Other Information: figs., tabs., refs; PBD: 2001
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD VESSELS; CRYSTALLOGRAPHY; DNA REPAIR; EXPERIMENTAL DATA; LEADING ABSTRACT; NEOPLASMS; POSITRON COMPUTED TOMOGRAPHY; PROGRESS REPORT; RADIOBIOLOGY; RADIOPHARMACEUTICALS; RADIOTHERAPY; RESEARCH PROGRAMS; SWISS LIGHT SOURCE; SWITZERLAND; TUMOR CELLS
OSTI ID:
20172544
Research Organizations:
Paul Scherrer Inst., CH-5232 Villigen PSI (Switzerland)
Country of Origin:
Switzerland
Language:
English
Other Identifying Numbers:
Other: ISSN 1423-7318; TRN: CH0100225030447
Availability:
Available from INIS in electronic form
Submitting Site:
CHN
Size:
78 pages
Announcement Date:
Jul 17, 2001

Citation Formats

Jaussi, Rolf, and Gschwend, Beatrice. Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences. Switzerland: N. p., 2001. Web.
Jaussi, Rolf, & Gschwend, Beatrice. Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences. Switzerland.
Jaussi, Rolf, and Gschwend, Beatrice. 2001. "Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences." Switzerland.
@misc{etde_20172544,
title = {Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences}
author = {Jaussi, Rolf, and Gschwend, Beatrice}
abstractNote = {The existing activities of the Department of Life Sciences have grown out of the specific know-how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know-how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development. The Institute of Medical Radiobiology analyses questions of the molecular biology of DNA repair. It is a joint activity of PSI and the University of Zurich. The newly established Structural Biology group is still in the build-up phase. A strong in-house research activity in macromolecular crystallography will complement the more user-oriented protein crystallography beam line, which is being built at the Swiss Light Source (SLS). In particular, tumour targeting by molecular vehicles and DNA repair are areas where structural information can provide important insights. Progress in 2000 in these topical areas is described in this report. A list of scientific publications in 2000 is also provided.}
place = {Switzerland}
year = {2001}
month = {Jul}
}