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Current status of neutron capture therapy

Abstract

There are about 6000 new glioblastoma multiform brain tumours diagnosed each year in the United States of America alone. This cancer is usually fatal within six months of diagnosis even with current standard treatments. Research on boron neutron capture therapy (BNCT) has been considered as a method of potentially curing such cancers. There is a great interest at under-utilised research reactors institutions to identify new medical utilization, attractive to the general public. Neutron capture therapy is a true multidisciplinary topic with a large variety of individuals involved. This publication attempts to provide current information for all those thinking about being involved with NCT, based on the knowledge and experience of those who have pioneered the treatment. It covers the whole range of NCT from designing reactor conversions or new facilities, through to clinical trials and their effectiveness. However, since most work has been done with boron capture therapy for brain tumours using modified thermal research reactors, this tends to be the focus of the report. One of the factors which need to be addressed at the beginning is the timing of the further development of NCT facilities. It should be emphasised that all current work is still at the research  More>>
Publication Date:
May 01, 2001
Product Type:
Technical Report
Report Number:
IAEA-TECDOC-1223
Reference Number:
EDB-01:060761
Resource Relation:
Other Information: Refs, figs, tabs; PBD: May 2001
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 22 GENERAL STUDIES OF NUCLEAR REACTORS; BORON; BRAIN; CARCINOMAS; DOSIMETRY; LEADING ABSTRACT; NEUTRON BEAMS; NEUTRON CAPTURE THERAPY; RADIATION DOSES; RADIOBIOLOGY; RESEARCH REACTORS
OSTI ID:
20172514
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 1011-4289; TRN: XA0101224030417
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
302 pages
Announcement Date:
Jul 17, 2001

Citation Formats

None. Current status of neutron capture therapy. IAEA: N. p., 2001. Web.
None. Current status of neutron capture therapy. IAEA.
None. 2001. "Current status of neutron capture therapy." IAEA.
@misc{etde_20172514,
title = {Current status of neutron capture therapy}
author = {None}
abstractNote = {There are about 6000 new glioblastoma multiform brain tumours diagnosed each year in the United States of America alone. This cancer is usually fatal within six months of diagnosis even with current standard treatments. Research on boron neutron capture therapy (BNCT) has been considered as a method of potentially curing such cancers. There is a great interest at under-utilised research reactors institutions to identify new medical utilization, attractive to the general public. Neutron capture therapy is a true multidisciplinary topic with a large variety of individuals involved. This publication attempts to provide current information for all those thinking about being involved with NCT, based on the knowledge and experience of those who have pioneered the treatment. It covers the whole range of NCT from designing reactor conversions or new facilities, through to clinical trials and their effectiveness. However, since most work has been done with boron capture therapy for brain tumours using modified thermal research reactors, this tends to be the focus of the report. One of the factors which need to be addressed at the beginning is the timing of the further development of NCT facilities. It should be emphasised that all current work is still at the research stage. Many of those now involved believe that there is little need for many more research facilities until such time as the treatment shows more promising results. For this and other reasons discussed in the report, very serious consideration should be given by research reactor owners and operators before spending large sums of money converting their facilities for NCT.}
place = {IAEA}
year = {2001}
month = {May}
}