Safety of nuclear reactors has been a central concern of the nuclear energy industry from the very beginning. This concern, and the resultant excellence of design, fabrication, and operation, aided by extensive engineered safety features, has given nuclear energy its superior record of protection of the environment and of the public health and safety. With respect to the fast reactor, it was recognized early in the program that there exists a theoretical possibility of a core compaction leading to significant energy release. The considerations of fission product effects are primarily on of the main concerns in evaluation of safety issues. Since fission products have the potential for dispersing fuel from the core region and thereby producing reactor shutdown, knowledge of their effects can contribute to demonstrating that there is a low probability producing whole-core involvement. Similarly, knowledge of fission product effects can contribute to demonstrating that there is a low probability of a whole-core disruptive accident leading to sufficient energy release to challenge the containment capability.