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Research and development on fusion zones in fiscal 1999. Third volume. Biomolecular mechanism and design; 1999 nendo yugo ryoiki kenkyu kaihatsu seika hokokusho. 3. Biomolecular mechanism and design

Abstract

It was intended to elucidate the structures of living organisms having excellent functions and the principles of these functions, and to create cells, structural bodies and molecular mechanisms that substitute these functions outside the bodies of the living organisms. Therefore, research and development has been performed on the fundamental technologies, whose achievements are compiled. In the research of creating cultured bones and cartilages, marrow cells and cartilage cells were cultured while providing physiological active materials and mechanical stimulation. Porous ceramics and porous biodegradating polymers coated with collagen were used as the substrate materials to have created artificial cartilages. In the research of structural change in a molecule motor, a low temperature electron microscope was used to make the structure visualized successfully for the first time. In the research of creating an artificial liver, the world's first cells like stem cells separated and refined from liver cells were cultured three dimensionally in a bio-reactor using special cultivation solution to have established the basic technology. In the research of libozyme, sensor function and high catalytic function were realized successfully in the cells by dimerizing libozymes. (NEDO)
Authors:
"NONE"
Publication Date:
Mar 01, 2000
Product Type:
Technical Report
Report Number:
JP-NEDO-010015325
Resource Relation:
Other Information: PBD: Mar 2000
Subject:
60 APPLIED LIFE SCIENCES; BIOTECHNOLOGY; MOLECULES; ANIMAL CELLS; BONE TISSUES; CULTIVATION; ARTIFICIAL ORGANS; CERAMICS; POROUS MATERIALS; COLLAGEN; COATINGS; BIODEGRADATION
OSTI ID:
20124461
Research Organizations:
New Energy and Industrial Technology Development Organization, Tokyo (Japan)
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
TRN: JN0041333
Availability:
Available to ETDE participating countries only(see www.etde.org); commercial reproduction prohibited; OSTI as DE20124461
Submitting Site:
NEDO
Size:
99 pages
Announcement Date:

Citation Formats

Research and development on fusion zones in fiscal 1999. Third volume. Biomolecular mechanism and design; 1999 nendo yugo ryoiki kenkyu kaihatsu seika hokokusho. 3. Biomolecular mechanism and design. Japan: N. p., 2000. Web.
Research and development on fusion zones in fiscal 1999. Third volume. Biomolecular mechanism and design; 1999 nendo yugo ryoiki kenkyu kaihatsu seika hokokusho. 3. Biomolecular mechanism and design. Japan.
2000. "Research and development on fusion zones in fiscal 1999. Third volume. Biomolecular mechanism and design; 1999 nendo yugo ryoiki kenkyu kaihatsu seika hokokusho. 3. Biomolecular mechanism and design." Japan.
@misc{etde_20124461,
title = {Research and development on fusion zones in fiscal 1999. Third volume. Biomolecular mechanism and design; 1999 nendo yugo ryoiki kenkyu kaihatsu seika hokokusho. 3. Biomolecular mechanism and design}
abstractNote = {It was intended to elucidate the structures of living organisms having excellent functions and the principles of these functions, and to create cells, structural bodies and molecular mechanisms that substitute these functions outside the bodies of the living organisms. Therefore, research and development has been performed on the fundamental technologies, whose achievements are compiled. In the research of creating cultured bones and cartilages, marrow cells and cartilage cells were cultured while providing physiological active materials and mechanical stimulation. Porous ceramics and porous biodegradating polymers coated with collagen were used as the substrate materials to have created artificial cartilages. In the research of structural change in a molecule motor, a low temperature electron microscope was used to make the structure visualized successfully for the first time. In the research of creating an artificial liver, the world's first cells like stem cells separated and refined from liver cells were cultured three dimensionally in a bio-reactor using special cultivation solution to have established the basic technology. In the research of libozyme, sensor function and high catalytic function were realized successfully in the cells by dimerizing libozymes. (NEDO)}
place = {Japan}
year = {2000}
month = {Mar}
}