Abstract
We describe a novel approach to treatment planning for heavy ion radiotherapy based on the local effect model (LEM) which allows to calculate the biologically effective dose not only for the target region but for the entire irradiation volume. LEM is ideally suited to be used as an integral part of treatment planning code systems for active dose shaping devices like the GSI raster scan system. Thus, it has been incorporated into our standard treatment planning system for ion therapy (TRiP). Single intensity modulated fields can be optimized with respect to homogeneous biologically effective dose. The relative biological effectiveness (RBE) is calculated separately for each voxel of the patient CT. Our radiobiologically oriented code system is in use since 1995 for the planning of irradiation experiments with cell cultures and animals such as rats and minipigs. Since 1997 it is in regular and successful use for patient treatment planning. (orig.)
Kraemer, M;
Scholz, M
[1]
- Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany). Biophysik
Citation Formats
Kraemer, M, and Scholz, M.
Treatment planning for heavy ion radiotherapy: calculation and optimization of biologically effective dose.
Germany: N. p.,
2000.
Web.
Kraemer, M, & Scholz, M.
Treatment planning for heavy ion radiotherapy: calculation and optimization of biologically effective dose.
Germany.
Kraemer, M, and Scholz, M.
2000.
"Treatment planning for heavy ion radiotherapy: calculation and optimization of biologically effective dose."
Germany.
@misc{etde_20119085,
title = {Treatment planning for heavy ion radiotherapy: calculation and optimization of biologically effective dose}
author = {Kraemer, M, and Scholz, M}
abstractNote = {We describe a novel approach to treatment planning for heavy ion radiotherapy based on the local effect model (LEM) which allows to calculate the biologically effective dose not only for the target region but for the entire irradiation volume. LEM is ideally suited to be used as an integral part of treatment planning code systems for active dose shaping devices like the GSI raster scan system. Thus, it has been incorporated into our standard treatment planning system for ion therapy (TRiP). Single intensity modulated fields can be optimized with respect to homogeneous biologically effective dose. The relative biological effectiveness (RBE) is calculated separately for each voxel of the patient CT. Our radiobiologically oriented code system is in use since 1995 for the planning of irradiation experiments with cell cultures and animals such as rats and minipigs. Since 1997 it is in regular and successful use for patient treatment planning. (orig.)}
place = {Germany}
year = {2000}
month = {Sep}
}
title = {Treatment planning for heavy ion radiotherapy: calculation and optimization of biologically effective dose}
author = {Kraemer, M, and Scholz, M}
abstractNote = {We describe a novel approach to treatment planning for heavy ion radiotherapy based on the local effect model (LEM) which allows to calculate the biologically effective dose not only for the target region but for the entire irradiation volume. LEM is ideally suited to be used as an integral part of treatment planning code systems for active dose shaping devices like the GSI raster scan system. Thus, it has been incorporated into our standard treatment planning system for ion therapy (TRiP). Single intensity modulated fields can be optimized with respect to homogeneous biologically effective dose. The relative biological effectiveness (RBE) is calculated separately for each voxel of the patient CT. Our radiobiologically oriented code system is in use since 1995 for the planning of irradiation experiments with cell cultures and animals such as rats and minipigs. Since 1997 it is in regular and successful use for patient treatment planning. (orig.)}
place = {Germany}
year = {2000}
month = {Sep}
}