Non destructive testing data from in-service inspections have specific features that require the most sophisticated techniques of signal and image processing. Each step in the overall information extraction process must be optimized by using recent approaches such like data decomposition and modelization, compression, sensor fusion and knowledge based systems. This can be achieved by means of wavelet transform, inverse problems formulation, standard compression algorithms, combined detection and estimation, neural networks and expert systems. These techniques are briefly presented through a number of Electricite de France applications or through recent literature results. (author). 1 fig., 20 refs.