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Impairment of blood lipids pattern in gamma irradiated albino mice and prophylactic role of thiols and W R-2721

Journal Article:

Abstract

The present work aims to investigate the effect of shot doses of whole body gamma irradiation at the levels, 6, 7.5, 11, 25 and 15 Gy, on the blood lipids pattern in male swiss albino mice. This has been manifested by the levels of total lipids, triglycerides, phospholipids and cholesterol. The radioprotective capacities of two sulfhydryl compounds: thiols and W R-2721, against impairment in blood lipids pattern, have been evaluated in mice received the higher shot radiation dose-level at 15 Gy. Significant increases in the levels of blood total lipid, phospholipids, triglycerides and cholesterol have been recorded on the third day post exposure under the experiment conditions, the data indicated more efficient protection of blood lipid pattern exerted by W R-2721 than in case of thiols. 2 figs., 2 tabs.
Authors:
EL-dighidy, E A.M.; El-Kady, M H.R. [1] 
  1. National Centre for Radiation Research and Technology, Atomic Energy Authority, Cairo, (Egypt)
Publication Date:
Dec 31, 1986
Product Type:
Journal Article
Reference Number:
SCA: 560152; PA: AIX-27:000930; EDB-96:031186; SN: 96001525519
Resource Relation:
Journal Name: Egyptian Journal of Radiation Sciences and Applications; Journal Volume: 7; Journal Issue: 2; Other Information: PBD: 1986
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; LIPIDS; RADIATION INJURIES; MICE; WHOLE-BODY IRRADIATION; BLOOD; CHOLESTEROL; EXPERIMENTAL DATA; PHOSPHOLIPIDS; RADIOPROTECTIVE SUBSTANCES; THIOLS; TRIGLYCERIDES
OSTI ID:
169122
Research Organizations:
Egyptian Society of Nuclear Sciences and Applications, Cairo (Egypt)
Country of Origin:
Egypt
Language:
English
Other Identifying Numbers:
Journal ID: EJRAES; TRN: EG9501557000930
Submitting Site:
INIS
Size:
pp. 169-179
Announcement Date:

Journal Article:

Citation Formats

EL-dighidy, E A.M., and El-Kady, M H.R. Impairment of blood lipids pattern in gamma irradiated albino mice and prophylactic role of thiols and W R-2721. Egypt: N. p., 1986. Web.
EL-dighidy, E A.M., & El-Kady, M H.R. Impairment of blood lipids pattern in gamma irradiated albino mice and prophylactic role of thiols and W R-2721. Egypt.
EL-dighidy, E A.M., and El-Kady, M H.R. 1986. "Impairment of blood lipids pattern in gamma irradiated albino mice and prophylactic role of thiols and W R-2721." Egypt.
@misc{etde_169122,
title = {Impairment of blood lipids pattern in gamma irradiated albino mice and prophylactic role of thiols and W R-2721}
author = {EL-dighidy, E A.M., and El-Kady, M H.R.}
abstractNote = {The present work aims to investigate the effect of shot doses of whole body gamma irradiation at the levels, 6, 7.5, 11, 25 and 15 Gy, on the blood lipids pattern in male swiss albino mice. This has been manifested by the levels of total lipids, triglycerides, phospholipids and cholesterol. The radioprotective capacities of two sulfhydryl compounds: thiols and W R-2721, against impairment in blood lipids pattern, have been evaluated in mice received the higher shot radiation dose-level at 15 Gy. Significant increases in the levels of blood total lipid, phospholipids, triglycerides and cholesterol have been recorded on the third day post exposure under the experiment conditions, the data indicated more efficient protection of blood lipid pattern exerted by W R-2721 than in case of thiols. 2 figs., 2 tabs.}
journal = {Egyptian Journal of Radiation Sciences and Applications}
issue = {2}
volume = {7}
journal type = {AC}
place = {Egypt}
year = {1986}
month = {Dec}
}