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Quality characteristics of chemicals for the radioimmunoassay of thyroxine and thyrotropin.; Caracteristicas de calidad de reactivos para el radioinmunoanalisis de tiroxina y tirotropina.

Abstract

Radioimmunoassay is a form of saturation analysis in which the test material competes with labelled antigen for a limited amount of antibody, the amount of label displaced being a measure of the antigen in the test sample. In this country, the kits for Radioimmunoassay (RIA) are imported, and this increase the cost of it. Because this lack of production, the National Institute of Nuclear Research (ININ) has developed RIA`s kits for the thyroxine (T{sub 4}), Thyrotropin (TSH) and Triyodotironine (T{sub 3}) hormones. This work presents the conclusions of the test recommended by the WHO. The quality test were: recuperation, cross reactions, basic parameters, intra and inter assay variations, sensibility and others. The results show that the RIA`s kits of the ININ have a good behavior and can be use in the clinical laboratory. (Author).
Authors:
Publication Date:
Dec 31, 1994
Product Type:
Thesis/Dissertation
Report Number:
INIS-mf-14598
Reference Number:
SCA: 553006; PA: AIX-26:069549; EDB-95:138332; ERA-20:030816; NTS-96:007124; SN: 95001471537
Resource Relation:
Other Information: TH: Thesis (Biologist).; PBD: 1994
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; RADIOIMMUNOASSAY; QUALITY CONTROL; THYROXINE; IODINE 125; LABELLED COMPOUNDS; LABELLING; QUALITY ASSURANCE; SENSITIVITY; TSH; WHO
OSTI ID:
110370
Research Organizations:
Universidad Nacional Autonoma de Mexico, Mexico City (Mexico). Facultad de Ciencias
Country of Origin:
Mexico
Language:
Spanish
Other Identifying Numbers:
Other: ON: DE96602627; TRN: MX9500017069549
Availability:
INIS; OSTI as DE96602627
Submitting Site:
INIS
Size:
72 p.
Announcement Date:
Oct 30, 1995

Citation Formats

Verdeja I, C E. Quality characteristics of chemicals for the radioimmunoassay of thyroxine and thyrotropin.; Caracteristicas de calidad de reactivos para el radioinmunoanalisis de tiroxina y tirotropina.. Mexico: N. p., 1994. Web.
Verdeja I, C E. Quality characteristics of chemicals for the radioimmunoassay of thyroxine and thyrotropin.; Caracteristicas de calidad de reactivos para el radioinmunoanalisis de tiroxina y tirotropina.. Mexico.
Verdeja I, C E. 1994. "Quality characteristics of chemicals for the radioimmunoassay of thyroxine and thyrotropin.; Caracteristicas de calidad de reactivos para el radioinmunoanalisis de tiroxina y tirotropina." Mexico.
@misc{etde_110370,
title = {Quality characteristics of chemicals for the radioimmunoassay of thyroxine and thyrotropin.; Caracteristicas de calidad de reactivos para el radioinmunoanalisis de tiroxina y tirotropina.}
author = {Verdeja I, C E}
abstractNote = {Radioimmunoassay is a form of saturation analysis in which the test material competes with labelled antigen for a limited amount of antibody, the amount of label displaced being a measure of the antigen in the test sample. In this country, the kits for Radioimmunoassay (RIA) are imported, and this increase the cost of it. Because this lack of production, the National Institute of Nuclear Research (ININ) has developed RIA`s kits for the thyroxine (T{sub 4}), Thyrotropin (TSH) and Triyodotironine (T{sub 3}) hormones. This work presents the conclusions of the test recommended by the WHO. The quality test were: recuperation, cross reactions, basic parameters, intra and inter assay variations, sensibility and others. The results show that the RIA`s kits of the ININ have a good behavior and can be use in the clinical laboratory. (Author).}
place = {Mexico}
year = {1994}
month = {Dec}
}