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Local radiation injuries of skin - prophylaxis and therapy

Abstract

The drug preparation `Nucliderm-gel` (BG patent document No. 68170/1984) is a gel formation containing native polynucleotide complex from thymus gland as an active component. The preparation is licensed in 1989 for production and usage by the Bulgarian Medical Drugs Commission. It has been applied in 43 patients (a total of 122 input fields) with acute or delayed radiodermatitis developed as a side effect after radiotherapy. The clinical surveillance of the skin reactions (erythema, edema, erosion, ulcer, skin atrophy and rhagades) show that this new preparation is a good stimulator of the granulation and epithelization processes. The drug has also a pronounced antiphlogistic and antinecrotic ability. (A.B.).
Publication Date:
Dec 31, 1992
Product Type:
Miscellaneous
Report Number:
INIS-mf-13834; CONF-9211296-
Reference Number:
SCA: 560151; PA: AIX-25:021763; EDB-94:058172; ERA-19:013281; NTS-94:017654; SN: 94001171539
Resource Relation:
Conference: National symposium on development and current problems of prophylaxis in Bulgaria,Lovech (Bulgaria),26-28 Nov 1992; Other Information: PBD: 1992
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; OINTMENTS; NUCLEOTIDES; POST-IRRADIATION THERAPY; RADIODERMATITIS; DRUGS; EXPERIMENTAL DATA; GELS; PATIENTS; SIDE EFFECTS; SKIN; THYMUS; 560151; MAN
OSTI ID:
10136387
Research Organizations:
Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya
Country of Origin:
Bulgaria
Language:
Bulgarian
Other Identifying Numbers:
Other: ON: DE94617857; TRN: BG9300378021763
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
4 p.
Announcement Date:
Apr 05, 1994

Citation Formats

Stefanova, D, Georgieva, R, and Pandova, V. Local radiation injuries of skin - prophylaxis and therapy. Bulgaria: N. p., 1992. Web.
Stefanova, D, Georgieva, R, & Pandova, V. Local radiation injuries of skin - prophylaxis and therapy. Bulgaria.
Stefanova, D, Georgieva, R, and Pandova, V. 1992. "Local radiation injuries of skin - prophylaxis and therapy." Bulgaria.
@misc{etde_10136387,
title = {Local radiation injuries of skin - prophylaxis and therapy}
author = {Stefanova, D, Georgieva, R, and Pandova, V}
abstractNote = {The drug preparation `Nucliderm-gel` (BG patent document No. 68170/1984) is a gel formation containing native polynucleotide complex from thymus gland as an active component. The preparation is licensed in 1989 for production and usage by the Bulgarian Medical Drugs Commission. It has been applied in 43 patients (a total of 122 input fields) with acute or delayed radiodermatitis developed as a side effect after radiotherapy. The clinical surveillance of the skin reactions (erythema, edema, erosion, ulcer, skin atrophy and rhagades) show that this new preparation is a good stimulator of the granulation and epithelization processes. The drug has also a pronounced antiphlogistic and antinecrotic ability. (A.B.).}
place = {Bulgaria}
year = {1992}
month = {Dec}
}