Abstract
Heavy charged particles are the most advanced tool of an external subcutane radiotherapy of deep seated tumors. Small angular- and lateral-scattering and the increase of the energy deposition with penetration depth are the physical basis for a more efficient tumor targeting. High biological efficiency in the tumor is the prerequisite for a successful treatment of tumors radioresistant against sparsely ionizing radiation. The possibility to perform target conform irradiation and to control the achieved/actual distribution using PET techniques guarantees that biological highly efficient stepping particles can be restricted to the tumor volume only. Although the physical and radiobiological properties of ion beams are very favourable for therapy, the necessity to produce these particles in an accelerator restricts a general application of heavy ions up to now. Presently the heavy ion accelerator SIS at GSI is the only source of heavy ion beams, sufficient in energy and intensity for therapy. A therapy unit is in preparation at GSI, the status of this project is given at the end of the paper. (orig.)
Citation Formats
Kraft, G, Haberer, T, Schardt, D, and Scholz, M.
Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy.
Germany: N. p.,
1993.
Web.
Kraft, G, Haberer, T, Schardt, D, & Scholz, M.
Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy.
Germany.
Kraft, G, Haberer, T, Schardt, D, and Scholz, M.
1993.
"Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy."
Germany.
@misc{etde_10135260,
title = {Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy}
author = {Kraft, G, Haberer, T, Schardt, D, and Scholz, M}
abstractNote = {Heavy charged particles are the most advanced tool of an external subcutane radiotherapy of deep seated tumors. Small angular- and lateral-scattering and the increase of the energy deposition with penetration depth are the physical basis for a more efficient tumor targeting. High biological efficiency in the tumor is the prerequisite for a successful treatment of tumors radioresistant against sparsely ionizing radiation. The possibility to perform target conform irradiation and to control the achieved/actual distribution using PET techniques guarantees that biological highly efficient stepping particles can be restricted to the tumor volume only. Although the physical and radiobiological properties of ion beams are very favourable for therapy, the necessity to produce these particles in an accelerator restricts a general application of heavy ions up to now. Presently the heavy ion accelerator SIS at GSI is the only source of heavy ion beams, sufficient in energy and intensity for therapy. A therapy unit is in preparation at GSI, the status of this project is given at the end of the paper. (orig.)}
place = {Germany}
year = {1993}
month = {Jul}
}
title = {Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy}
author = {Kraft, G, Haberer, T, Schardt, D, and Scholz, M}
abstractNote = {Heavy charged particles are the most advanced tool of an external subcutane radiotherapy of deep seated tumors. Small angular- and lateral-scattering and the increase of the energy deposition with penetration depth are the physical basis for a more efficient tumor targeting. High biological efficiency in the tumor is the prerequisite for a successful treatment of tumors radioresistant against sparsely ionizing radiation. The possibility to perform target conform irradiation and to control the achieved/actual distribution using PET techniques guarantees that biological highly efficient stepping particles can be restricted to the tumor volume only. Although the physical and radiobiological properties of ion beams are very favourable for therapy, the necessity to produce these particles in an accelerator restricts a general application of heavy ions up to now. Presently the heavy ion accelerator SIS at GSI is the only source of heavy ion beams, sufficient in energy and intensity for therapy. A therapy unit is in preparation at GSI, the status of this project is given at the end of the paper. (orig.)}
place = {Germany}
year = {1993}
month = {Jul}
}