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Establishment of optimal thermal neutron capture therapy for 5 types of human malignant melanoma

Abstract

A series of boron neutron capture therapy (BNCT) studies has already germinated in 1972, with a view to establishing the BNCT particularly suited for the treatment of various types of malignant melanoma, and has been succeeded by research teams comprised of multi-disciplinary members. Twelve patients (7 men and 5 women, aged from 50 to 85 years) with malignant melanoma have been treated with BNCT; among them, six patients were completely cured, four had extremely reduced tumors, and two were still in the clinical process. The present Progress Report is a compilation of 39 research presentations for the recent two years. In this report, three patients are described. Of these, one patient had deep-seated lesions in right and left lymph nodes. These lesions were cured by the use of D{sub 2}O that allowed neutron beams to reach them. Application of positron emission tomography to the diagnosis of melanoma is a highlight in this Report. (N.K.).
Authors:
Mishima, Yutaka [1] 
  1. ed.; Mishima Inst. for Dermatological Research, Kobe (Japan)
Publication Date:
Mar 01, 1993
Product Type:
Technical Report
Report Number:
KURRI-TR-374
Reference Number:
SCA: 550604; PA: JPN-94:001218; EDB-94:047568; ERA-19:013164; NTS-94:018258; SN: 94001163927
Resource Relation:
Other Information: PBD: Mar 1993
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MELANOMAS; NEUTRON CAPTURE THERAPY; BORON 10; KUR REACTOR; OPTIMIZATION; FLUORINE 18; POSITRON COMPUTED TOMOGRAPHY; PATIENTS; HAMSTERS; TISSUE DISTRIBUTION; AFFINITY; PHANTOMS; DEPTH DOSE DISTRIBUTIONS; RADIOSENSITIVITY; RADIATION DOSES; LYMPH NODES; BORON COMPOUNDS; RBE; SHIELDING; 550604; UNSEALED RADIONUCLIDES IN THERAPY
OSTI ID:
10131695
Research Organizations:
Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.
Country of Origin:
Japan
Language:
Japanese;English
Other Identifying Numbers:
Other: ON: DE94748703; TRN: JP9401218
Availability:
OSTI; NTIS; INIS
Submitting Site:
JPN
Size:
280 p.
Announcement Date:
Jul 04, 2005

Citation Formats

Mishima, Yutaka. Establishment of optimal thermal neutron capture therapy for 5 types of human malignant melanoma. Japan: N. p., 1993. Web.
Mishima, Yutaka. Establishment of optimal thermal neutron capture therapy for 5 types of human malignant melanoma. Japan.
Mishima, Yutaka. 1993. "Establishment of optimal thermal neutron capture therapy for 5 types of human malignant melanoma." Japan.
@misc{etde_10131695,
title = {Establishment of optimal thermal neutron capture therapy for 5 types of human malignant melanoma}
author = {Mishima, Yutaka}
abstractNote = {A series of boron neutron capture therapy (BNCT) studies has already germinated in 1972, with a view to establishing the BNCT particularly suited for the treatment of various types of malignant melanoma, and has been succeeded by research teams comprised of multi-disciplinary members. Twelve patients (7 men and 5 women, aged from 50 to 85 years) with malignant melanoma have been treated with BNCT; among them, six patients were completely cured, four had extremely reduced tumors, and two were still in the clinical process. The present Progress Report is a compilation of 39 research presentations for the recent two years. In this report, three patients are described. Of these, one patient had deep-seated lesions in right and left lymph nodes. These lesions were cured by the use of D{sub 2}O that allowed neutron beams to reach them. Application of positron emission tomography to the diagnosis of melanoma is a highlight in this Report. (N.K.).}
place = {Japan}
year = {1993}
month = {Mar}
}