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Evaluation of radioprotective properties of chlorophyllin against the gamma-rays; Investigacion de las propiedades radioprotectoras de la clorofilina ante los rayos gamma

Abstract

Several decades ago it had been demonstrated that chlorophyllin, and its water soluble derivates, such as chlorophyllin, have therapeutic values. recently an antimutagenic activity has been observed in several tests. The aim of this work is to investigate if chlorophyllin has some radioprotective effect when the organisms are exposed to gamma-rays. The somatic mutation and recombination test in drosophila was used. This test allows us to detect simultaneously both genetic mutation, chromosomal aberration and mitotic recombination. The conduction of the experiment involved four treatments: (1) 5% sucrose, (2) 5% chlorophyllin, (3) 5% sucrose +20Gy{gamma}rays (4) 5% chlorophyllin +20Gy{gamma}rays. All the treatments lasted 24 hours and three replicas were performed. The data obtained showed a significant decrease in spot frequency found in the treatment with chlorophyllin and {gamma} rays. From the results we are to conclude that the chlorophyllin has a radioprotective effect, when the drosophila larvae are irradiated with 20 Gy OF {gamma}rays. Mitotic recombination was affected in the same way and it is important because genetic recombination process are related to cancer induction. (Author).
Publication Date:
Dec 31, 1991
Product Type:
Thesis/Dissertation
Report Number:
INIS-mf-13140
Reference Number:
SCA: 560152; PA: AIX-23:025513; SN: 92000685307
Resource Relation:
Other Information: TH: Thesis (Bach. Sci.).; PBD: 1991
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DROSOPHILA; RADIOPROTECTIVE SUBSTANCES; CHROMOSOMAL ABERRATIONS; EXPERIMENTAL DATA; GAMMA RADIATION; GENE RECOMBINATION; GENETIC RADIATION EFFECTS; LARVAE; 560152; ANIMALS
OSTI ID:
10130201
Research Organizations:
Universidad Nacional Autonoma de Mexico, Mexico City (Mexico). Facultad de Ciencias
Country of Origin:
Mexico
Language:
Spanish
Other Identifying Numbers:
Other: ON: DE92620248; TRN: MX9200013025513
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
56 p.
Announcement Date:
Jul 04, 2005

Citation Formats

Hernandez-Gutierrez, M E. Evaluation of radioprotective properties of chlorophyllin against the gamma-rays; Investigacion de las propiedades radioprotectoras de la clorofilina ante los rayos gamma. Mexico: N. p., 1991. Web.
Hernandez-Gutierrez, M E. Evaluation of radioprotective properties of chlorophyllin against the gamma-rays; Investigacion de las propiedades radioprotectoras de la clorofilina ante los rayos gamma. Mexico.
Hernandez-Gutierrez, M E. 1991. "Evaluation of radioprotective properties of chlorophyllin against the gamma-rays; Investigacion de las propiedades radioprotectoras de la clorofilina ante los rayos gamma." Mexico.
@misc{etde_10130201,
title = {Evaluation of radioprotective properties of chlorophyllin against the gamma-rays; Investigacion de las propiedades radioprotectoras de la clorofilina ante los rayos gamma}
author = {Hernandez-Gutierrez, M E}
abstractNote = {Several decades ago it had been demonstrated that chlorophyllin, and its water soluble derivates, such as chlorophyllin, have therapeutic values. recently an antimutagenic activity has been observed in several tests. The aim of this work is to investigate if chlorophyllin has some radioprotective effect when the organisms are exposed to gamma-rays. The somatic mutation and recombination test in drosophila was used. This test allows us to detect simultaneously both genetic mutation, chromosomal aberration and mitotic recombination. The conduction of the experiment involved four treatments: (1) 5% sucrose, (2) 5% chlorophyllin, (3) 5% sucrose +20Gy{gamma}rays (4) 5% chlorophyllin +20Gy{gamma}rays. All the treatments lasted 24 hours and three replicas were performed. The data obtained showed a significant decrease in spot frequency found in the treatment with chlorophyllin and {gamma} rays. From the results we are to conclude that the chlorophyllin has a radioprotective effect, when the drosophila larvae are irradiated with 20 Gy OF {gamma}rays. Mitotic recombination was affected in the same way and it is important because genetic recombination process are related to cancer induction. (Author).}
place = {Mexico}
year = {1991}
month = {Dec}
}