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Dante-Z sequence as selective impulsion in high field mono and multidimensional NMR. Application to the study of proteins, peptides and their interactions; Utilisation de la sequence Dante-Z comme impulsion selective en RMN haute resolution mono et multidimensionnelle. Application a l`etude des proteines, des peptides et de leurs interactions

Abstract

DANTE-Z is a simple and efficient way for NMR spectral selection. We present here different applications of DANTE-Z in high-resolution NMR of peptides and proteins. We have been using proton selective excitation by DANTE-Z to perform 1D-correlated (homo- or heteronuclear) experiments corresponding to one line of either 2D or 3D experiments. Following the same scheme, we could also edit planes of 3D experiments by concatenating 1D-correlated experiments with conventional 2D experiments. In the heteronuclear case (i.e. {sup 1}H, {sup 31}P), we could also edit planes of a 4D experiment by the simultaneous selection of {sup 1}H and the X nucleus. Owing to the favourable excitation profile of DANTE-Z, we used it successfully for topological excitations (spectral width from 150 Hz up to 1500 Hz) in `semi-soft`-2D experiments and `soft`-2D experiment. These applications are illustrated by the results obtained at 600 MHz on a protein and a phosphonamide peptide.
Authors:
Roumestand, C; Toma, F; [1]  Boudot, D [2] 
  1. CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Direction des Sciences du Vivant
  2. Nancy-1 Univ., 54 (France)
Publication Date:
Dec 31, 1992
Product Type:
Technical Report
Report Number:
CEA-R-5608
Reference Number:
SCA: 553006; PA: AIX-24:026483; SN: 93000950971
Resource Relation:
Other Information: PBD: 1992
Subject:
60 APPLIED LIFE SCIENCES; NUCLEAR MAGNETIC RESONANCE; PROTONS; EXCITATION; FOUR-DIMENSIONAL CALCULATIONS; NMR IMAGING; NMR SPECTROMETERS; PEPTIDES; PROTEIN STRUCTURE; PROTEINS; PULSE GENERATORS; PULSE TECHNIQUES; SPATIAL RESOLUTION; STRUCTURAL CHEMICAL ANALYSIS; THREE-DIMENSIONAL CALCULATIONS; TWO-DIMENSIONAL CALCULATIONS; 553006; OTHER AGRICULTURAL APPLICATIONS
OSTI ID:
10129401
Research Organizations:
CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Direction des Sciences du Vivant
Country of Origin:
France
Language:
French
Other Identifying Numbers:
Other: ON: DE93618208; TRN: FR9300757026483
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
FRN
Size:
[59] p.
Announcement Date:
Jul 04, 2005

Citation Formats

Roumestand, C, Toma, F, and Boudot, D. Dante-Z sequence as selective impulsion in high field mono and multidimensional NMR. Application to the study of proteins, peptides and their interactions; Utilisation de la sequence Dante-Z comme impulsion selective en RMN haute resolution mono et multidimensionnelle. Application a l`etude des proteines, des peptides et de leurs interactions. France: N. p., 1992. Web.
Roumestand, C, Toma, F, & Boudot, D. Dante-Z sequence as selective impulsion in high field mono and multidimensional NMR. Application to the study of proteins, peptides and their interactions; Utilisation de la sequence Dante-Z comme impulsion selective en RMN haute resolution mono et multidimensionnelle. Application a l`etude des proteines, des peptides et de leurs interactions. France.
Roumestand, C, Toma, F, and Boudot, D. 1992. "Dante-Z sequence as selective impulsion in high field mono and multidimensional NMR. Application to the study of proteins, peptides and their interactions; Utilisation de la sequence Dante-Z comme impulsion selective en RMN haute resolution mono et multidimensionnelle. Application a l`etude des proteines, des peptides et de leurs interactions." France.
@misc{etde_10129401,
title = {Dante-Z sequence as selective impulsion in high field mono and multidimensional NMR. Application to the study of proteins, peptides and their interactions; Utilisation de la sequence Dante-Z comme impulsion selective en RMN haute resolution mono et multidimensionnelle. Application a l`etude des proteines, des peptides et de leurs interactions}
author = {Roumestand, C, Toma, F, and Boudot, D}
abstractNote = {DANTE-Z is a simple and efficient way for NMR spectral selection. We present here different applications of DANTE-Z in high-resolution NMR of peptides and proteins. We have been using proton selective excitation by DANTE-Z to perform 1D-correlated (homo- or heteronuclear) experiments corresponding to one line of either 2D or 3D experiments. Following the same scheme, we could also edit planes of 3D experiments by concatenating 1D-correlated experiments with conventional 2D experiments. In the heteronuclear case (i.e. {sup 1}H, {sup 31}P), we could also edit planes of a 4D experiment by the simultaneous selection of {sup 1}H and the X nucleus. Owing to the favourable excitation profile of DANTE-Z, we used it successfully for topological excitations (spectral width from 150 Hz up to 1500 Hz) in `semi-soft`-2D experiments and `soft`-2D experiment. These applications are illustrated by the results obtained at 600 MHz on a protein and a phosphonamide peptide.}
place = {France}
year = {1992}
month = {Dec}
}