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Experimental radiotherapy unit to be established at GSI in Darmstadt; Einrichtung einer experimentellen Strahlentherapie bei der Gesellschaft fuer Schwerionenforschung, Darmstadt

Technical Report:

Abstract

The Radiologische Universitaetsklinik, Heidelberg, the Gesellschaft fuer Schwerionenforschung, GSI, Darmstadt, and the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, have filed an application for a joint project intended to study the feasibility and methodology of an enhancement of radiotherapy by way of application of heavy ions and novel irradiation techniques. The experimental radiotherapy unit is to be installed at the heavy ion synchrotron of GSI. It is planned to have about 70 patients a year taking part in the clinical study extending over a period of five years. The results obtained shall be analysed to answer the following questions: - Is the technique developed suitable for clinical routine? - Are the improved dose distributions obtained with the charged particles more effective for local tumor healing than the radiation applied for conventional radiotherapy? - Can an additional clinical effect be attributed to the high-LET properties of the heavy charged particles? - Do the results indicate novel applications of the high-precision radiotherapy using heavy ions? The project is also intended to yield baseline data for defining the concept and technical conditions of heavy-ion radiotherapy as a clinical routine method and therefore also encompasses a design study for a heavy-ion accelerator exclusively for clinical applications. (orig./MG)  More>>
Authors:
Kraft, G; [1]  Gademann, G [1] 
  1. comp.
Publication Date:
May 01, 1993
Product Type:
Technical Report
Report Number:
GSI-93-23
Reference Number:
SCA: 550603; 560101; PA: DEN-94:0F0753; EDB-94:027135; ERA-19:007493; NTS-94:015132; SN: 94001136200
Resource Relation:
Other Information: PBD: May 1993
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 61 RADIATION PROTECTION AND DOSIMETRY; RADIOTHERAPY; RESEARCH PROGRAMS; HEAVY IONS; ION BEAMS; SYNCHROTRONS; PATIENTS; THERAPEUTIC USES; RADIATION DOSE DISTRIBUTIONS; NEOPLASMS; LET; ACCURACY; 550603; 560101; EXTERNAL RADIATION IN THERAPY; DOSIMETRY AND MONITORING
OSTI ID:
10119858
Research Organizations:
Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Heidelberg Univ., Mannheim (Germany). Inst. fuer Klinische Radiologie; Deutsches Krebsforschungszentrum, Heidelberg (Germany)
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: ISSN 0171-4546; Other: ON: DE94734094; TRN: DE94F0753
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
DEN
Size:
94 p.
Announcement Date:
Jun 30, 2005

Technical Report:

Citation Formats

Kraft, G, and Gademann, G. Experimental radiotherapy unit to be established at GSI in Darmstadt; Einrichtung einer experimentellen Strahlentherapie bei der Gesellschaft fuer Schwerionenforschung, Darmstadt. Germany: N. p., 1993. Web.
Kraft, G, & Gademann, G. Experimental radiotherapy unit to be established at GSI in Darmstadt; Einrichtung einer experimentellen Strahlentherapie bei der Gesellschaft fuer Schwerionenforschung, Darmstadt. Germany.
Kraft, G, and Gademann, G. 1993. "Experimental radiotherapy unit to be established at GSI in Darmstadt; Einrichtung einer experimentellen Strahlentherapie bei der Gesellschaft fuer Schwerionenforschung, Darmstadt." Germany.
@misc{etde_10119858,
title = {Experimental radiotherapy unit to be established at GSI in Darmstadt; Einrichtung einer experimentellen Strahlentherapie bei der Gesellschaft fuer Schwerionenforschung, Darmstadt}
author = {Kraft, G, and Gademann, G}
abstractNote = {The Radiologische Universitaetsklinik, Heidelberg, the Gesellschaft fuer Schwerionenforschung, GSI, Darmstadt, and the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, have filed an application for a joint project intended to study the feasibility and methodology of an enhancement of radiotherapy by way of application of heavy ions and novel irradiation techniques. The experimental radiotherapy unit is to be installed at the heavy ion synchrotron of GSI. It is planned to have about 70 patients a year taking part in the clinical study extending over a period of five years. The results obtained shall be analysed to answer the following questions: - Is the technique developed suitable for clinical routine? - Are the improved dose distributions obtained with the charged particles more effective for local tumor healing than the radiation applied for conventional radiotherapy? - Can an additional clinical effect be attributed to the high-LET properties of the heavy charged particles? - Do the results indicate novel applications of the high-precision radiotherapy using heavy ions? The project is also intended to yield baseline data for defining the concept and technical conditions of heavy-ion radiotherapy as a clinical routine method and therefore also encompasses a design study for a heavy-ion accelerator exclusively for clinical applications. (orig./MG) [Deutsch] Die Radiologische Universitaetsklinik Heidelberg, die Gesellschaft fuer Schwerionenforschung Darmstadt (GSI) und das Deutsche Krebsforschungszentrum Heidelberg (DKFZ) legen einen gemeinsamen Projektantrag vor mit dem Ziel, eine Verbesserung der Strahlentherapie durch die Anwendung von schweren Ionen und neuen Bestrahlungstechniken zu erreichen. Geplant ist der Aufbau einer experimentellen Strahlentherapie-Einheit am Schwerionensynchrotron der GSI. Anhand der Ergebnisse von etwa 70 behandelten Patienten pro Jahr sollen nach einer fuenfjaehrigen klinischen Phase folgende Fragen beantwortet werden: - Ist die entwickelte Technik geeignet fuer eine klinische Routine? - Laesst sich mit den besseren Dosisverteilungen von geladenen Teilchen die lokale Tumorheilung im Vergleich zu konventionellen Strahlen guensig beeinflussen? - Hat die Hoch-LET-Eigenschaft schwerer geladener Teilchen eine klinisch erkennbare zusaetzliche Wirkung? - Lassen sich neue Indikationen fuer die hochpraezise Strahlentherapie mit schweren Ionen finden? Das Projekt ist als Vorbereitung einer Schwerionenstrahlentherapie fuer die allgemeine Patientenversorgung in einer Klinik geplant. Daher wird eine Design-Studie zu einem ausschliesslich klinisch genutzten Schwerionenbeschleuniger in das Projekt integriert. (orig./MG)}
place = {Germany}
year = {1993}
month = {May}
}