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Biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemoluminescence

Abstract

Utilizing lymphocyte chemiluminescence technique, the biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemiluminescence (Ly-CL) stimulated with PHA or ConA in vitro were investigated. The results showed: (1) 0.25 Gy {sup 60}Co {gamma}-ray irradiation showed a tendency to increase (P > 0.05), 0.5 Gy showed significant increase in Ly-CL(p < 0.05), 1 Gy produced significant suppression (P < 0.01). (2) 2{approx}16 Gy {sup 60}Co {gamma}-ray irradiation also expressed suppressive effects on Ly-CL caused by two different concentration of ConA (50 100 {mu}g/mL)(P < 0.01). Linear regression analysis showed that there was a significant correlation between the intensity of Ly-CL and irradiation dose (P < 0.0005). (3) 2{approx}16 Gy {sup 60}Co {gamma}-ray irradiation failed to produce suppressive effects on Ly-CL time (P > 0.05).
Authors:
Zijun, Mao; Xiao, Su [1] 
  1. Suzhou Medical Coll. (China)
Publication Date:
Nov 01, 1991
Product Type:
Technical Report
Report Number:
CNIC-00551; SMC-0067.
Reference Number:
SCA: 560120; PA: AIX-24:005759; SN: 93000930894
Resource Relation:
Other Information: PBD: Nov 1991
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LYMPHOCYTES; BIOLOGICAL RADIATION EFFECTS; CHEMILUMINESCENCE; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; PHYTOHEMAGGLUTININ; 560120; RADIATION EFFECTS ON BIOCHEMICALS, CELLS, AND TISSUE CULTURE
OSTI ID:
10118802
Research Organizations:
China Nuclear Information Centre, Beijing, BJ (China)
Country of Origin:
China
Language:
English
Other Identifying Numbers:
Other: ON: DE93611421; ISBN 7-5022-0588-8; TRN: CN9201687005759
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
[8] p.
Announcement Date:
Jun 30, 2005

Citation Formats

Zijun, Mao, and Xiao, Su. Biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemoluminescence. China: N. p., 1991. Web.
Zijun, Mao, &amp; Xiao, Su. Biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemoluminescence. China.
Zijun, Mao, and Xiao, Su. 1991. "Biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemoluminescence." China.
@misc{etde_10118802,
title = {Biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemoluminescence}
author = {Zijun, Mao, and Xiao, Su}
abstractNote = {Utilizing lymphocyte chemiluminescence technique, the biological effects of {sup 60}Co {gamma}-ray irradiation on lymphocyte chemiluminescence (Ly-CL) stimulated with PHA or ConA in vitro were investigated. The results showed: (1) 0.25 Gy {sup 60}Co {gamma}-ray irradiation showed a tendency to increase (P > 0.05), 0.5 Gy showed significant increase in Ly-CL(p < 0.05), 1 Gy produced significant suppression (P < 0.01). (2) 2{approx}16 Gy {sup 60}Co {gamma}-ray irradiation also expressed suppressive effects on Ly-CL caused by two different concentration of ConA (50 100 {mu}g/mL)(P < 0.01). Linear regression analysis showed that there was a significant correlation between the intensity of Ly-CL and irradiation dose (P < 0.0005). (3) 2{approx}16 Gy {sup 60}Co {gamma}-ray irradiation failed to produce suppressive effects on Ly-CL time (P > 0.05).}
place = {China}
year = {1991}
month = {Nov}
}