Abstract
By using an improved fluorometric method with 2-thiobarbituric acid (TBA) as fluorometric agent, the antiradiation effects of four kinds of antioxidants on {sup 60}Co {gamma}-ray irradiation inducing final products of lipid peroxides (LPO), i.e. malodialdehyde (MDA) content changes in human blood lymphocytes, were investigated with LPO value as an indicator. The results of the experiment were as following: (1)The radioprotective effect of exogenous antioxidants added to human blood lymphocytes on radiation-induced LPO damage of cellular membrane were remarkable; (2)The radioprotective beneficial sequences of four kinds of antioxidants were arranged like this: SOD > VE >VC, Se{sup 4+}; (3)Radioprotective effects of antioxidants on radiation-induced damage varied especially with the property of antioxidants, drug concentration, and pretreatment and monitoring time, etc., as well as irradiated dosage and various kinds of incubated cells. In addition, the mechanism of these antioxidants as radioprotectants on human blood lymphocytes is discussed in connection with LPO damage and radioprotection.
Citation Formats
Mingsuo, Wang, Xuandi, Gu, Genbo, Zhu, Jixing, Feng, and Liaoyuan, Su.
Radioprotective effect of antioxidants on human blood lymphocytes.
China: N. p.,
1991.
Web.
Mingsuo, Wang, Xuandi, Gu, Genbo, Zhu, Jixing, Feng, & Liaoyuan, Su.
Radioprotective effect of antioxidants on human blood lymphocytes.
China.
Mingsuo, Wang, Xuandi, Gu, Genbo, Zhu, Jixing, Feng, and Liaoyuan, Su.
1991.
"Radioprotective effect of antioxidants on human blood lymphocytes."
China.
@misc{etde_10118798,
title = {Radioprotective effect of antioxidants on human blood lymphocytes}
author = {Mingsuo, Wang, Xuandi, Gu, Genbo, Zhu, Jixing, Feng, and Liaoyuan, Su}
abstractNote = {By using an improved fluorometric method with 2-thiobarbituric acid (TBA) as fluorometric agent, the antiradiation effects of four kinds of antioxidants on {sup 60}Co {gamma}-ray irradiation inducing final products of lipid peroxides (LPO), i.e. malodialdehyde (MDA) content changes in human blood lymphocytes, were investigated with LPO value as an indicator. The results of the experiment were as following: (1)The radioprotective effect of exogenous antioxidants added to human blood lymphocytes on radiation-induced LPO damage of cellular membrane were remarkable; (2)The radioprotective beneficial sequences of four kinds of antioxidants were arranged like this: SOD > VE >VC, Se{sup 4+}; (3)Radioprotective effects of antioxidants on radiation-induced damage varied especially with the property of antioxidants, drug concentration, and pretreatment and monitoring time, etc., as well as irradiated dosage and various kinds of incubated cells. In addition, the mechanism of these antioxidants as radioprotectants on human blood lymphocytes is discussed in connection with LPO damage and radioprotection.}
place = {China}
year = {1991}
month = {Sep}
}
title = {Radioprotective effect of antioxidants on human blood lymphocytes}
author = {Mingsuo, Wang, Xuandi, Gu, Genbo, Zhu, Jixing, Feng, and Liaoyuan, Su}
abstractNote = {By using an improved fluorometric method with 2-thiobarbituric acid (TBA) as fluorometric agent, the antiradiation effects of four kinds of antioxidants on {sup 60}Co {gamma}-ray irradiation inducing final products of lipid peroxides (LPO), i.e. malodialdehyde (MDA) content changes in human blood lymphocytes, were investigated with LPO value as an indicator. The results of the experiment were as following: (1)The radioprotective effect of exogenous antioxidants added to human blood lymphocytes on radiation-induced LPO damage of cellular membrane were remarkable; (2)The radioprotective beneficial sequences of four kinds of antioxidants were arranged like this: SOD > VE >VC, Se{sup 4+}; (3)Radioprotective effects of antioxidants on radiation-induced damage varied especially with the property of antioxidants, drug concentration, and pretreatment and monitoring time, etc., as well as irradiated dosage and various kinds of incubated cells. In addition, the mechanism of these antioxidants as radioprotectants on human blood lymphocytes is discussed in connection with LPO damage and radioprotection.}
place = {China}
year = {1991}
month = {Sep}
}