Some of the important research and development (R and D) activities carried out at the Centre during the last two or three years are described in brief. The descriptions are arranged under the headings : Physical Sciences, Chemical Sciences, Material and Materials Science, Radioisotopes, Reactors, Fuel Cycle, Radiological Safety and Protection, Electronics and Instrumentation, Engineering Services, and Life Sciences. The text is illustrated with a number of photographs - some of them coloured. (M.G.B.).