Abstract
Background: Although computer-aided evaluation (CAE) programs were introduced to help differentiate benign tumors from malignant ones, the set of CAE-measured parameters that best predict malignancy have not yet been established. Purpose: To assess the value of the central washout sign on CAE color overlay images of breast MRI. Material and Methods: We evaluated the frequency of the central washout sign using CAE. The central washout sign was determined so that thin, rim-like, persistent kinetics were seen in the periphery of the tumor. Then, sequentially, plateau and washout kinetics appeared. Two additional CAE-delayed kinetic variables were compared with the central washout sign for assessment of diagnostic utility: the predominant enhancement type (washout, plateau, or persistent) and the most suspicious enhancement type (any washout > any plateau > any persistent kinetics). Results: One hundred and forty-nine pathologically proven breast lesions (130 malignant, 19 benign) were evaluated. A central washout sign was associated with 87% of malignant lesions but only 11% of benign lesions. Significant differences were found when delayed-phase kinetics were categorized by the most suspicious enhancement type (P< 0.001) and the presence of the central washout sign (P< 0.001). Under the criteria of the most suspicious kinetics, 68% of benign lesions
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Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com;
Choi, Hye Young;
[1]
Lee, Byung Hee;
[2]
Noh, Woo-Chul;
[3]
Kim, Rock Bum
[4]
- Dept. of Radiology, Gyeongsang National Univ. Hospital, Jinju (Korea, Republic of)
- Dept. of Radiology, Korea Cancer Centre Hospital, Seoul (Korea, Republic of)
- Dept. of Surgery, Korea Cancer Centre Hospital, Seoul (Korea, Republic of)
- Dept. of Preventive Medicine, Gyeongsang National Univ., Jinju (Korea, Republic of)
Citation Formats
Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com, Choi, Hye Young, Lee, Byung Hee, Noh, Woo-Chul, and Kim, Rock Bum.
Central washout sign in computer-aided evaluation of breast MRI: preliminary results.
Sweden: N. p.,
2011.
Web.
doi:10.1258/AR.2010.100187.
Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com, Choi, Hye Young, Lee, Byung Hee, Noh, Woo-Chul, & Kim, Rock Bum.
Central washout sign in computer-aided evaluation of breast MRI: preliminary results.
Sweden.
https://doi.org/10.1258/AR.2010.100187
Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com, Choi, Hye Young, Lee, Byung Hee, Noh, Woo-Chul, and Kim, Rock Bum.
2011.
"Central washout sign in computer-aided evaluation of breast MRI: preliminary results."
Sweden.
https://doi.org/10.1258/AR.2010.100187.
@misc{etde_1011581,
title = {Central washout sign in computer-aided evaluation of breast MRI: preliminary results}
author = {Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com, Choi, Hye Young, Lee, Byung Hee, Noh, Woo-Chul, and Kim, Rock Bum}
abstractNote = {Background: Although computer-aided evaluation (CAE) programs were introduced to help differentiate benign tumors from malignant ones, the set of CAE-measured parameters that best predict malignancy have not yet been established. Purpose: To assess the value of the central washout sign on CAE color overlay images of breast MRI. Material and Methods: We evaluated the frequency of the central washout sign using CAE. The central washout sign was determined so that thin, rim-like, persistent kinetics were seen in the periphery of the tumor. Then, sequentially, plateau and washout kinetics appeared. Two additional CAE-delayed kinetic variables were compared with the central washout sign for assessment of diagnostic utility: the predominant enhancement type (washout, plateau, or persistent) and the most suspicious enhancement type (any washout > any plateau > any persistent kinetics). Results: One hundred and forty-nine pathologically proven breast lesions (130 malignant, 19 benign) were evaluated. A central washout sign was associated with 87% of malignant lesions but only 11% of benign lesions. Significant differences were found when delayed-phase kinetics were categorized by the most suspicious enhancement type (P< 0.001) and the presence of the central washout sign (P< 0.001). Under the criteria of the most suspicious kinetics, 68% of benign lesions were assigned as plateau or washout pattern. Conclusion: The central washout sign is a reliable indicator of malignancy on CAE color overlay images of breast MRI}
doi = {10.1258/AR.2010.100187}
journal = []
issue = {3}
volume = {52}
place = {Sweden}
year = {2011}
month = {Apr}
}
title = {Central washout sign in computer-aided evaluation of breast MRI: preliminary results}
author = {Ko, Eun Sook (Dept. of Radiology, Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)), e-mail: mathilda0330@gmail.com, Choi, Hye Young, Lee, Byung Hee, Noh, Woo-Chul, and Kim, Rock Bum}
abstractNote = {Background: Although computer-aided evaluation (CAE) programs were introduced to help differentiate benign tumors from malignant ones, the set of CAE-measured parameters that best predict malignancy have not yet been established. Purpose: To assess the value of the central washout sign on CAE color overlay images of breast MRI. Material and Methods: We evaluated the frequency of the central washout sign using CAE. The central washout sign was determined so that thin, rim-like, persistent kinetics were seen in the periphery of the tumor. Then, sequentially, plateau and washout kinetics appeared. Two additional CAE-delayed kinetic variables were compared with the central washout sign for assessment of diagnostic utility: the predominant enhancement type (washout, plateau, or persistent) and the most suspicious enhancement type (any washout > any plateau > any persistent kinetics). Results: One hundred and forty-nine pathologically proven breast lesions (130 malignant, 19 benign) were evaluated. A central washout sign was associated with 87% of malignant lesions but only 11% of benign lesions. Significant differences were found when delayed-phase kinetics were categorized by the most suspicious enhancement type (P< 0.001) and the presence of the central washout sign (P< 0.001). Under the criteria of the most suspicious kinetics, 68% of benign lesions were assigned as plateau or washout pattern. Conclusion: The central washout sign is a reliable indicator of malignancy on CAE color overlay images of breast MRI}
doi = {10.1258/AR.2010.100187}
journal = []
issue = {3}
volume = {52}
place = {Sweden}
year = {2011}
month = {Apr}
}