You need JavaScript to view this

Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors

Abstract

Background: Accurate preoperative diagnosis of fat scanty angiomyolipomas is an important clinical issue. By evaluating the low signal intensity of angiomyolipomas in MR T2-weighted images the diagnostic accuracy can be elevated. Purpose: To retrospectively assess the usefulness of T2-weighted MR imaging for differentiating low-fat angiomyolipomas (AMLs) from other renal tumors. Material and Methods: We retrospectively evaluated 71 patients with surgically proven renal masses (10 AMLs, 57 renal cell carcinomas [RCCs], and four oncocytomas), all of which showed no visible fat as well as gradual enhancement patterns on contrast-enhanced CT. Signal intensity was measured in each renal mass and in the spleen on T2-weighted images, and each signal intensity ratio (SIR) was calculated; SIR values were then compared in the AML and non-AML groups. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of the two parameters for differentiating the two groups. Results: The SIR values (77 +- 24% vs. 162 +- 79%, p = 0.002) were significantly lower in the AML than in the non-AML group. The area under the ROC curve was 0.926 for SIR. The sensitivity and specificity in the diagnosis of AMLs were 90% and 90.2%, using SIR cut-off of 92.5%. Conclusion: Signal intensity  More>>
Authors:
Choi, Hyuck Jae; Kim, Jeong Kon; Kim, Mi-Hyun; Cho, Kyoung-Sik; [1]  Ahn, Hanjong; Kim, Choung-Soo [2] 
  1. Dept. of Radiology, Asan Medical Center, Univ. of Ulsan (Korea, Republic of)
  2. Dept. of Urology, Asan Medical Center, Univ. of Ulsan (Korea, Republic of)
Publication Date:
Apr 15, 2011
Product Type:
Journal Article
Resource Relation:
Journal Name: Acta Radiologica (online); Journal Volume: 52; Journal Issue: 3; Other Information: refs., figs., tabs.; 10.1258/AR.2010.090491
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; NMR IMAGING; NEOPLASMS; KIDNEYS
OSTI ID:
1011575
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1600-0455; TRN: SE1108063
Availability:
Available from DOI: http://dx.doi.org/10.1258/ar.2010.090491
Submitting Site:
SWDN
Size:
page(s) 349-353
Announcement Date:
Apr 25, 2011

Citation Formats

Choi, Hyuck Jae, Kim, Jeong Kon, Kim, Mi-Hyun, Cho, Kyoung-Sik, Ahn, Hanjong, and Kim, Choung-Soo. Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors. Sweden: N. p., 2011. Web. doi:10.1258/AR.2010.090491.
Choi, Hyuck Jae, Kim, Jeong Kon, Kim, Mi-Hyun, Cho, Kyoung-Sik, Ahn, Hanjong, & Kim, Choung-Soo. Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors. Sweden. doi:10.1258/AR.2010.090491.
Choi, Hyuck Jae, Kim, Jeong Kon, Kim, Mi-Hyun, Cho, Kyoung-Sik, Ahn, Hanjong, and Kim, Choung-Soo. 2011. "Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors." Sweden. doi:10.1258/AR.2010.090491. https://www.osti.gov/servlets/purl/10.1258/AR.2010.090491.
@misc{etde_1011575,
title = {Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors}
author = {Choi, Hyuck Jae, Kim, Jeong Kon, Kim, Mi-Hyun, Cho, Kyoung-Sik, Ahn, Hanjong, and Kim, Choung-Soo}
abstractNote = {Background: Accurate preoperative diagnosis of fat scanty angiomyolipomas is an important clinical issue. By evaluating the low signal intensity of angiomyolipomas in MR T2-weighted images the diagnostic accuracy can be elevated. Purpose: To retrospectively assess the usefulness of T2-weighted MR imaging for differentiating low-fat angiomyolipomas (AMLs) from other renal tumors. Material and Methods: We retrospectively evaluated 71 patients with surgically proven renal masses (10 AMLs, 57 renal cell carcinomas [RCCs], and four oncocytomas), all of which showed no visible fat as well as gradual enhancement patterns on contrast-enhanced CT. Signal intensity was measured in each renal mass and in the spleen on T2-weighted images, and each signal intensity ratio (SIR) was calculated; SIR values were then compared in the AML and non-AML groups. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of the two parameters for differentiating the two groups. Results: The SIR values (77 +- 24% vs. 162 +- 79%, p = 0.002) were significantly lower in the AML than in the non-AML group. The area under the ROC curve was 0.926 for SIR. The sensitivity and specificity in the diagnosis of AMLs were 90% and 90.2%, using SIR cut-off of 92.5%. Conclusion: Signal intensity measurements on T2-weighted MR images can differentiate AML from non-AML in the kidney}
doi = {10.1258/AR.2010.090491}
journal = {Acta Radiologica (online)}
issue = {3}
volume = {52}
place = {Sweden}
year = {2011}
month = {Apr}
}