The purpose of this study is to suggest a rational method of analysis for the fluid-structure interaction of a spent fuel storage pool under earthquake loading taking into consideration of the structural responses obtained from various analysis methods and modeling techniques. A literature review, an introduction of the theory of fluid-structure interaction, a presentation of several analytical and finite element models, a comparison of the results from each model are included. For the dynamic analysis of the spent fuel storage pool three uncoupled and four coupled models are considered and response spectrum analysis method and time history analysis method are used. Based on the results of the study on various analysis models, the coupled model which utilizes the chracteristics of contact surface is concluded as the most reasonable one for the analysis of fluid-structure interaction. (Author).