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Comparative study of internal contamination of different radiators in skeleton on induction of mutagenic effect in bone marrow cells

Technical Report:

Abstract

The purpose of the present study was to ascertain comparative retention of {sup 134}Cs or {sup 147}Pm in skeleton on induction of chromosome aberrations and PCE`s micronucleus formation in bone marrow cells. Results indicated that after iv signal nuclide {sup 134}Cs, through 7 weeks observation, the retention data in skeleton could be well described by an exponential expression. Experiments indicated that the retention value and the absorption dose of {sup 147}Pm in skeleton were significantly higher in comparison with {sup 134}Cs. Both internal contamination of {sup 134}Cs or {sup 147}Pm could induce chromosome aberrations and PCE`s micronucleus formation in bone marrow cells. Among the type of chromosome aberrations of bone marrow cells induced by {sup 134}Cs or {sup 147}Pm included gap, chromatid breakage, chromosome breakage and translocation. Moreover, the chromosome aberration rates were elevated when the intake of radioactivity of {sup 134}Cs or {sup 147}Pm were enlarged. At the same time, chromosome fragment of bone marrow cells also induced by {sup 134}Cs or {sup 147}Pm only through high radioactive contamination. Studies showed that chromosome translocation was appeared only through high radioactivity of {sup 147}Pm contamination. By comparing with {sup 1}`4{sup 7}Pm, however, the induction of chromosome aberrations and PCE`s micronucleus  More>>
Authors:
Shoupeng, Zhu; Liuyi, Wang; Weidong, Yang [1] 
  1. Suzhou Medical Coll., JS (China)
Publication Date:
Oct 01, 1990
Product Type:
Technical Report
Report Number:
CNIC-00433; SMC-0047.
Reference Number:
SCA: 560162; PA: AIX-23:011177; SN: 92000637779
Resource Relation:
Other Information: PBD: Oct 1990
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE MARROW CELLS; CHROMOSOMAL ABERRATIONS; MUTATIONS; CESIUM 134; BIOLOGICAL RADIATION EFFECTS; PROMETHIUM 147; BONE TISSUES; CELL NUCLEI; MORPHOLOGICAL CHANGES; RADIONUCLIDE KINETICS; RETENTION; 560162; ANIMALS, PLANTS, MICROORGANISMS, AND CELLS
OSTI ID:
10111390
Research Organizations:
China Nuclear Information Centre, Beijing, BJ (China)
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Other: ON: DE92613546; TRN: CN9101693011177
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
9 p.
Announcement Date:
Jun 30, 2005

Technical Report:

Citation Formats

Shoupeng, Zhu, Liuyi, Wang, and Weidong, Yang. Comparative study of internal contamination of different radiators in skeleton on induction of mutagenic effect in bone marrow cells. China: N. p., 1990. Web.
Shoupeng, Zhu, Liuyi, Wang, & Weidong, Yang. Comparative study of internal contamination of different radiators in skeleton on induction of mutagenic effect in bone marrow cells. China.
Shoupeng, Zhu, Liuyi, Wang, and Weidong, Yang. 1990. "Comparative study of internal contamination of different radiators in skeleton on induction of mutagenic effect in bone marrow cells." China.
@misc{etde_10111390,
title = {Comparative study of internal contamination of different radiators in skeleton on induction of mutagenic effect in bone marrow cells}
author = {Shoupeng, Zhu, Liuyi, Wang, and Weidong, Yang}
abstractNote = {The purpose of the present study was to ascertain comparative retention of {sup 134}Cs or {sup 147}Pm in skeleton on induction of chromosome aberrations and PCE`s micronucleus formation in bone marrow cells. Results indicated that after iv signal nuclide {sup 134}Cs, through 7 weeks observation, the retention data in skeleton could be well described by an exponential expression. Experiments indicated that the retention value and the absorption dose of {sup 147}Pm in skeleton were significantly higher in comparison with {sup 134}Cs. Both internal contamination of {sup 134}Cs or {sup 147}Pm could induce chromosome aberrations and PCE`s micronucleus formation in bone marrow cells. Among the type of chromosome aberrations of bone marrow cells induced by {sup 134}Cs or {sup 147}Pm included gap, chromatid breakage, chromosome breakage and translocation. Moreover, the chromosome aberration rates were elevated when the intake of radioactivity of {sup 134}Cs or {sup 147}Pm were enlarged. At the same time, chromosome fragment of bone marrow cells also induced by {sup 134}Cs or {sup 147}Pm only through high radioactive contamination. Studies showed that chromosome translocation was appeared only through high radioactivity of {sup 147}Pm contamination. By comparing with {sup 1}`4{sup 7}Pm, however, the induction of chromosome aberrations and PCE`s micronucleus formation rates on bone marrow cells induced by {sup 134}Cs was quite low.}
place = {China}
year = {1990}
month = {Oct}
}