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Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis

Technical Report:

Abstract

The purpose of the present study is to ascertain {sup 147}Pm retention in testis and its radiogenotoxicological effects of gene mutation through varying radioactivities of internal exposure. Especially the accumulation of {sup 147}Pm in testis induces the dominant lethal, dominant skeletal mutation and abnormalities in sperm. Studies indicated that the cumulative absorption dose in testis increases as the internal exposure of {sup 147}Pm increases. The internal exposure of {sup 147}Pm can destroy the genetic materials and raise the rates of dominant lethal and dominant mutation of skeletal abnormalities in the offspring. The relationship between the rate of dominant skeletal mutation (B) and accumulated radioactivities of {sup 147}Pm (D) in testis can be described by a linear equation that is B 20.68 + 35.48 D. The relationship between abnormalities of the sperm and the cumulative dose from {sup 147}Pm in testis can be expressed by the following equation: S = 10.8705 D{sup 0.5224} + 3.1768.
Authors:
Shoupeng, Zhu; Mingyue, Lun; Shuqin, Yang [1] 
  1. Suzhou Medical Coll., JS (China)
Publication Date:
May 01, 1990
Product Type:
Technical Report
Report Number:
CNIC-00408; SMC-0044.
Reference Number:
SCA: 560162; PA: AIX-23:011174; SN: 92000637776
Resource Relation:
Other Information: PBD: May 1990
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; PROMETHIUM 147; BIOLOGICAL RADIATION EFFECTS; SPERMATOZOA; GENE MUTATIONS; DOSE-RESPONSE RELATIONSHIPS; MALFORMATIONS; MUTATION FREQUENCY; RETENTION; TESTES; 560162; ANIMALS, PLANTS, MICROORGANISMS, AND CELLS
OSTI ID:
10111380
Research Organizations:
China Nuclear Information Centre, Beijing, BJ (China)
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Other: ON: DE92613543; TRN: CN9101704011174
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
7 p.
Announcement Date:
Jun 30, 2005

Technical Report:

Citation Formats

Shoupeng, Zhu, Mingyue, Lun, and Shuqin, Yang. Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis. China: N. p., 1990. Web.
Shoupeng, Zhu, Mingyue, Lun, & Shuqin, Yang. Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis. China.
Shoupeng, Zhu, Mingyue, Lun, and Shuqin, Yang. 1990. "Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis." China.
@misc{etde_10111380,
title = {Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis}
author = {Shoupeng, Zhu, Mingyue, Lun, and Shuqin, Yang}
abstractNote = {The purpose of the present study is to ascertain {sup 147}Pm retention in testis and its radiogenotoxicological effects of gene mutation through varying radioactivities of internal exposure. Especially the accumulation of {sup 147}Pm in testis induces the dominant lethal, dominant skeletal mutation and abnormalities in sperm. Studies indicated that the cumulative absorption dose in testis increases as the internal exposure of {sup 147}Pm increases. The internal exposure of {sup 147}Pm can destroy the genetic materials and raise the rates of dominant lethal and dominant mutation of skeletal abnormalities in the offspring. The relationship between the rate of dominant skeletal mutation (B) and accumulated radioactivities of {sup 147}Pm (D) in testis can be described by a linear equation that is B 20.68 + 35.48 D. The relationship between abnormalities of the sperm and the cumulative dose from {sup 147}Pm in testis can be expressed by the following equation: S = 10.8705 D{sup 0.5224} + 3.1768.}
place = {China}
year = {1990}
month = {May}
}