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Effects of heavy particles on cellular DNA - measurement of DNA base damage

Abstract

It is now assumed that nucleic acids are one of the major targets of the deleterious effects of cosmic radiation and particularly of charged heavy particles having a TEL higher than 50 keV/{mu}m. This may be inferred from numerous spatial experiments involving various biological materials. The author explains how the importance of DNA in the biological effects of heavy ions has been shown, from ground experiments by using acceleration of particles.
Authors:
Publication Date:
Dec 01, 1993
Product Type:
Conference
Report Number:
CEA-CONF-11497; CONF-9303244-
Reference Number:
SCA: 560120; PA: AIX-25:002570; EDB-94:015374; ERA-19:005373; NTS-94:014054; SN: 93001120139
Resource Relation:
Conference: 6. cospar colloquium on radiation risk in humans on exploratory missions in space,Bad Honnef (Germany),11-14 Mar 1993; Other Information: PBD: 1993
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DNA; COSMIC RADIATION; GENETIC RADIATION EFFECTS; HEAVY IONS; RADIATION INJURIES; RISK ASSESSMENT; STRAND BREAKS; 560120; RADIATION EFFECTS ON BIOCHEMICALS, CELLS, AND TISSUE CULTURE
OSTI ID:
10109554
Research Organizations:
CEA Centre d`Etudes de Grenoble, 38 (France). Dept. de Recherche Fondamentale sur la Matiere Condensee
Country of Origin:
France
Language:
English
Other Identifying Numbers:
Other: ON: DE94608875; TRN: FR9303755002570
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
FRN
Size:
4 p.
Announcement Date:
Jun 30, 2005

Citation Formats

Cadet, J. Effects of heavy particles on cellular DNA - measurement of DNA base damage. France: N. p., 1993. Web.
Cadet, J. Effects of heavy particles on cellular DNA - measurement of DNA base damage. France.
Cadet, J. 1993. "Effects of heavy particles on cellular DNA - measurement of DNA base damage." France.
@misc{etde_10109554,
title = {Effects of heavy particles on cellular DNA - measurement of DNA base damage}
author = {Cadet, J}
abstractNote = {It is now assumed that nucleic acids are one of the major targets of the deleterious effects of cosmic radiation and particularly of charged heavy particles having a TEL higher than 50 keV/{mu}m. This may be inferred from numerous spatial experiments involving various biological materials. The author explains how the importance of DNA in the biological effects of heavy ions has been shown, from ground experiments by using acceleration of particles.}
place = {France}
year = {1993}
month = {Dec}
}