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Long-term MRI findings of patients with embolized cerebral aneurysms

Abstract

Background: Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. Parenchymal infarctions related to aneurysms have mostly been studied in patients with subarachnoidal hemorrhage (SAH) but infarction rates in patients with endovascularly treated unruptured aneurysms have been little studied. Purpose: To determine the frequency of permanent parenchymal lesions as detected in magnetic resonance imaging (MRI) in patients treated with endovascular coiling and to assess aneurysm-related infarctions after the initial treatment period. Material and Methods: A total of 64 patients (32 with primarily ruptured aneurysms) with 69 embolized aneurysms were examined neurologically and by MRI and magnetic resonance angiography (MRA) more than 9 years after the initial endovascular treatment. Results: A total of 14 out of 32 (44%) SAH patients and 11 (34%) patients with unruptured aneurysms had parenchymal lesions in MRI. Infarctions were detected in 10 (31%) SAH patients and the majority (9/10, 90%) of them were aneurysm-related. All aneurysm-related infarctions were detected at the acute hospitalization stage. A total of six (55%) out of 11 infarctions in patients with unruptured aneurysms were aneurysm-related and two of them appeared after the treatment period. Patients with infarction had poorer clinical outcome than patients with no ischemic  More>>
Publication Date:
Feb 15, 2011
Product Type:
Journal Article
Resource Relation:
Journal Name: Acta Radiologica (online); Journal Volume: 52; Journal Issue: 2; Other Information: 28 refs., 6 figs., 3 tabs.; 10.1258/AR.2010.100127
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CENTRAL NERVOUS SYSTEM; NMR IMAGING; BLOOD CIRCULATION; EMBOLI
OSTI ID:
1010779
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1600-0455; TRN: SE1108049
Availability:
Available from DOI: http://dx.doi.org/10.1258/ar.2010.100127
Submitting Site:
SWDN
Size:
page(s) 204-210
Announcement Date:
Apr 11, 2011

Citation Formats

Pyysalo, Liisa M, Niskakangas, Tero T, Oehman, Juha E. (Tampere Univ. Hospital, Dept. of Neurosurgery, Tampere (Finland)), email: liisa.pyysalo@uta.fi, Keski-Nisula, Leo H, and Kaehaerae, Veikko J. Long-term MRI findings of patients with embolized cerebral aneurysms. Sweden: N. p., 2011. Web. doi:10.1258/AR.2010.100127.
Pyysalo, Liisa M, Niskakangas, Tero T, Oehman, Juha E. (Tampere Univ. Hospital, Dept. of Neurosurgery, Tampere (Finland)), email: liisa.pyysalo@uta.fi, Keski-Nisula, Leo H, & Kaehaerae, Veikko J. Long-term MRI findings of patients with embolized cerebral aneurysms. Sweden. doi:10.1258/AR.2010.100127.
Pyysalo, Liisa M, Niskakangas, Tero T, Oehman, Juha E. (Tampere Univ. Hospital, Dept. of Neurosurgery, Tampere (Finland)), email: liisa.pyysalo@uta.fi, Keski-Nisula, Leo H, and Kaehaerae, Veikko J. 2011. "Long-term MRI findings of patients with embolized cerebral aneurysms." Sweden. doi:10.1258/AR.2010.100127. https://www.osti.gov/servlets/purl/10.1258/AR.2010.100127.
@misc{etde_1010779,
title = {Long-term MRI findings of patients with embolized cerebral aneurysms}
author = {Pyysalo, Liisa M, Niskakangas, Tero T, Oehman, Juha E. (Tampere Univ. Hospital, Dept. of Neurosurgery, Tampere (Finland)), email: liisa.pyysalo@uta.fi, Keski-Nisula, Leo H, and Kaehaerae, Veikko J}
abstractNote = {Background: Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. Parenchymal infarctions related to aneurysms have mostly been studied in patients with subarachnoidal hemorrhage (SAH) but infarction rates in patients with endovascularly treated unruptured aneurysms have been little studied. Purpose: To determine the frequency of permanent parenchymal lesions as detected in magnetic resonance imaging (MRI) in patients treated with endovascular coiling and to assess aneurysm-related infarctions after the initial treatment period. Material and Methods: A total of 64 patients (32 with primarily ruptured aneurysms) with 69 embolized aneurysms were examined neurologically and by MRI and magnetic resonance angiography (MRA) more than 9 years after the initial endovascular treatment. Results: A total of 14 out of 32 (44%) SAH patients and 11 (34%) patients with unruptured aneurysms had parenchymal lesions in MRI. Infarctions were detected in 10 (31%) SAH patients and the majority (9/10, 90%) of them were aneurysm-related. All aneurysm-related infarctions were detected at the acute hospitalization stage. A total of six (55%) out of 11 infarctions in patients with unruptured aneurysms were aneurysm-related and two of them appeared after the treatment period. Patients with infarction had poorer clinical outcome than patients with no ischemic lesions in MRI. Conclusion: Nineteen percent of patients with unruptured and 41% with ruptured aneurysms had aneurysmrelated parenchymal lesions in MRI. Most of these were detected during acute treatment period. Aneurysmrelated infarctions after treatment period are uncommon}
doi = {10.1258/AR.2010.100127}
journal = {Acta Radiologica (online)}
issue = {2}
volume = {52}
place = {Sweden}
year = {2011}
month = {Feb}
}