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The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques

Abstract

The aim of this review is to examine the recent literature on using advanced magnetic resonance imaging (MRI) techniques for finding neuroimaging biomarkers that are sensitive to the detection of risks for Alzheimer's disease (AD). Since structural MRI techniques, such as brain structural volumetry and voxel based morphometry (VBM), have been widely used for AD studies and extensively reviewed, we will only briefly touch on the topics of volumetry and morphometry. The focus of the current review is about the more recent developments in the search for AD neuroimaging biomarkers with functional MRI (fMRI), resting-state functional connectivity MRI (fcMRI), diffusion tensor imaging (DTI), arterial spin-labeling (ASL), and magnetic resonance spectroscopy (MRS)
Authors:
Li, Tie-Qiang; [1]  Wahlund, Lars-Olof [2] 
  1. Karolinska Huddinge - Medical Physics, Stockholm (Sweden)
  2. Dept. of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm (Sweden)
Publication Date:
Feb 15, 2011
Product Type:
Journal Article
Resource Relation:
Journal Name: Acta Radiologica (online); Journal Volume: 52; Journal Issue: 2; Other Information: 106 refs., 5 figs.; 10.1258/AR.2010.100053
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; NMR IMAGING; REVIEWS; DIAGNOSTIC TECHNIQUES; NERVOUS SYSTEM DISEASES
OSTI ID:
1010778
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1600-0455; TRN: SE1108048
Availability:
Available from DOI: http://dx.doi.org/10.1258/ar.2010.100053
Submitting Site:
SWDN
Size:
page(s) 211-222
Announcement Date:
Apr 11, 2011

Citation Formats

Li, Tie-Qiang, and Wahlund, Lars-Olof. The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques. Sweden: N. p., 2011. Web. doi:10.1258/AR.2010.100053.
Li, Tie-Qiang, & Wahlund, Lars-Olof. The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques. Sweden. doi:10.1258/AR.2010.100053.
Li, Tie-Qiang, and Wahlund, Lars-Olof. 2011. "The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques." Sweden. doi:10.1258/AR.2010.100053. https://www.osti.gov/servlets/purl/10.1258/AR.2010.100053.
@misc{etde_1010778,
title = {The search for neuroimaging biomarkers of Alzheimer's disease with advanced MRI techniques}
author = {Li, Tie-Qiang, and Wahlund, Lars-Olof}
abstractNote = {The aim of this review is to examine the recent literature on using advanced magnetic resonance imaging (MRI) techniques for finding neuroimaging biomarkers that are sensitive to the detection of risks for Alzheimer's disease (AD). Since structural MRI techniques, such as brain structural volumetry and voxel based morphometry (VBM), have been widely used for AD studies and extensively reviewed, we will only briefly touch on the topics of volumetry and morphometry. The focus of the current review is about the more recent developments in the search for AD neuroimaging biomarkers with functional MRI (fMRI), resting-state functional connectivity MRI (fcMRI), diffusion tensor imaging (DTI), arterial spin-labeling (ASL), and magnetic resonance spectroscopy (MRS)}
doi = {10.1258/AR.2010.100053}
journal = {Acta Radiologica (online)}
issue = {2}
volume = {52}
place = {Sweden}
year = {2011}
month = {Feb}
}