Abstract
In this first report it is described the synthesis, separation and purification of the 2-radioiodinated histamine ``125 I-labelled histamine by a mixed anhydride reaction. About 75% incorporation of I``1125, from Na``125, I, was achieved with a molecular ratio of 1:1 mixed anhydride:histamine. The radiochemical purity of the conjugate by TLC was >99% and its theoretical specific activity, 3850 mu Ci/mug. Dissolved in ethanol and held at -20 degree centigree under darkness decomposition on storage did not exceed 1% per month.
Citation Formats
Suarez, C, Simon, M A, Paz, D, and Romero del Hombrebueno, B.
Optimization of the synthesis of a high specific activity ``125 I-labelled hapten for radioimmunoassays; Optimizacion de un metodo de preparacion de un radiohapteno -``125 I para ria de alta actividad especifica.
Spain: N. p.,
1994.
Web.
Suarez, C, Simon, M A, Paz, D, & Romero del Hombrebueno, B.
Optimization of the synthesis of a high specific activity ``125 I-labelled hapten for radioimmunoassays; Optimizacion de un metodo de preparacion de un radiohapteno -``125 I para ria de alta actividad especifica.
Spain.
Suarez, C, Simon, M A, Paz, D, and Romero del Hombrebueno, B.
1994.
"Optimization of the synthesis of a high specific activity ``125 I-labelled hapten for radioimmunoassays; Optimizacion de un metodo de preparacion de un radiohapteno -``125 I para ria de alta actividad especifica."
Spain.
@misc{etde_10104672,
title = {Optimization of the synthesis of a high specific activity ``125 I-labelled hapten for radioimmunoassays; Optimizacion de un metodo de preparacion de un radiohapteno -``125 I para ria de alta actividad especifica}
author = {Suarez, C, Simon, M A, Paz, D, and Romero del Hombrebueno, B}
abstractNote = {In this first report it is described the synthesis, separation and purification of the 2-radioiodinated histamine ``125 I-labelled histamine by a mixed anhydride reaction. About 75% incorporation of I``1125, from Na``125, I, was achieved with a molecular ratio of 1:1 mixed anhydride:histamine. The radiochemical purity of the conjugate by TLC was >99% and its theoretical specific activity, 3850 mu Ci/mug. Dissolved in ethanol and held at -20 degree centigree under darkness decomposition on storage did not exceed 1% per month.}
place = {Spain}
year = {1994}
month = {Dec}
}
title = {Optimization of the synthesis of a high specific activity ``125 I-labelled hapten for radioimmunoassays; Optimizacion de un metodo de preparacion de un radiohapteno -``125 I para ria de alta actividad especifica}
author = {Suarez, C, Simon, M A, Paz, D, and Romero del Hombrebueno, B}
abstractNote = {In this first report it is described the synthesis, separation and purification of the 2-radioiodinated histamine ``125 I-labelled histamine by a mixed anhydride reaction. About 75% incorporation of I``1125, from Na``125, I, was achieved with a molecular ratio of 1:1 mixed anhydride:histamine. The radiochemical purity of the conjugate by TLC was >99% and its theoretical specific activity, 3850 mu Ci/mug. Dissolved in ethanol and held at -20 degree centigree under darkness decomposition on storage did not exceed 1% per month.}
place = {Spain}
year = {1994}
month = {Dec}
}